P. falciparum Invasion and Erythrocyte Aging
| Title: | P. falciparum Invasion and Erythrocyte Aging |
|---|---|
| Authors: | María Fernanda Alves-Rosa; Nicole M. Tayler; Doriana Dorta; Lorena M. Coronado; Carmenza Spadafora |
| Source: | Cells, Vol 13, Iss 4, p 334 (2024) |
| Publisher Information: | MDPI AG |
| Publication Year: | 2024 |
| Collection: | Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: | Plasmodium; erythrocyte; senescence; deformability; invasion; receptors; Cytology; QH573-671 |
| Description: | Plasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell. Both characteristics change with the maturation of erythrocytes. Some Plasmodia prefer younger vs. older erythrocytes. How does the life evolution of the RBC affect the invasion of the parasite? What happens when the RBC ages? In this review, we present what is known up until now. |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | https://www.mdpi.com/2073-4409/13/4/334; https://doaj.org/toc/2073-4409; https://doaj.org/article/e1e1345993b34776a7be8de6e678e871 |
| DOI: | 10.3390/cells13040334 |
| Availability: | https://doi.org/10.3390/cells13040334; https://doaj.org/article/e1e1345993b34776a7be8de6e678e871 |
| Accession Number: | edsbas.244FA673 |
| Database: | BASE |