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Morphological features of organelles during apoptosis: An overview

Title: Morphological features of organelles during apoptosis: An overview
Authors: Bottone MG; Santin G; Aredia F; Bernocchi G; Pellicciari C; Scovassi AI.
Source: Cells 2 (2013): 294–305. doi:10.3390/cells2020294 ; info:cnr-pdr/source/autori:Bottone MG, Santin G, Aredia F, Bernocchi G, Pellicciari C, Scovassi AI./titolo:Morphological features of organelles during apoptosis: An overview/doi:10.3390cells2020294/rivista:Cells/anno:2013/pagina_da:294/pagina_a:305/intervallo_pagine:294–305/volume:2
Publisher Information: Molecular Diversity Preservation International, Basel
Publication Year: 2013
Collection: PUMAlab (ISTI CNR - Consiglio Nazionale delle Ricerche / National Research Council)
Subject Terms: apoptosis; cytoskeleton; endoplasmic reticulum; Golgi apparatus; lysosomes; mitochondria
Description: An apoptotic program leading to controlled cell dismantling implies perturbations of nuclear dynamics, as well as changes affecting the organelle structure and distribution. In human cancer cells driven to apoptosis by different stimuli, we have recently investigated the morphological properties of several organelles, including mitochondria, lysosomes, endoplasmic reticulum and Golgi apparatus. In this review, we will discuss the body of evidence in the literature suggesting that organelles are generally relocated and/or degraded during apoptosis, irrespectively of the apoptogenic stimulus and cell type.
Document Type: article in journal/newspaper
Language: English
Relation: info:cnr-pdr/author/idpersonaleesterno:10/BOTTONE/MARIA GRAZIA; info:cnr-pdr/author/matricola:19184/SCOVASSI/ANNA; http://www.cnr.it/prodotto/i/270696; https://publications.cnr.it/doc/270696; https://dx.doi.org/10.3390/cells2020294; info:doi:10.3390/cells2020294
DOI: 10.3390/cells2020294
Availability: http://www.cnr.it/prodotto/i/270696; https://publications.cnr.it/doc/270696; https://doi.org/10.3390/cells2020294
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.24CACD66
Database: BASE