| Title: |
Long-Term Left Ventricular Remodeling of Patients With Hypertrophic Cardiomyopathy |
| Authors: |
Musumeci MB; RUSSO, DOMITILLA; Limite LR; Canepa M; Tini G; Casenghi M; FRANCIA, Pietro; ADDUCI, CARMEN; Pagannone E; Magrì D; Volpe M; Autore C. |
| Contributors: |
Musumeci, Mb; Russo, Domitilla; Limite, Lr; Canepa, M; Tini, G; Casenghi, M; Francia, Pietro; Adduci, Carmen; Pagannone, E; Magrì, D; Volpe, M; Autore, C. |
| Publisher Information: |
Elsevier Inc. |
| Publication Year: |
2018 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
hypertrophic cardiomyopathy; LV remodeling; end-stage HC; apical aneurysm |
| Description: |
In hypertrophic cardiomyopathy (HC), a process of left ventricular (LV) remodeling carrying an adverse prognosis has been described. Conversely, a gradual and benign LV wall thinning has been suggested but never investigated. Therefore, we studied a HC cohort over a long period of time to evaluate the occurrence of a LV remodeling with a benign clinical course. Data of HC patients aged 18 to 65years and without any condition known to influence LV remodeling were analyzed over a mean follow-up of 7.6 ± 5.7 years. Of 231 HC patients (65% males, mean age 46 ± 12 years), 47 (20%) developed LV remodeling, of whom 23 (10%) had a thinning ≥15% of LV maximal wall thickness from baseline without systolic dysfunction (MWT thinning); 13 (6%) progressed to a LV ejection fraction |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/30293658; info:eu-repo/semantics/altIdentifier/wos/WOS:000453637000017; volume:122; issue:11; firstpage:1924; lastpage:1931; numberofpages:8; journal:THE AMERICAN JOURNAL OF CARDIOLOGY; http://hdl.handle.net/11573/1182985 |
| DOI: |
10.1016/j.amjcard.2018.08.041 |
| Availability: |
http://hdl.handle.net/11573/1182985; https://doi.org/10.1016/j.amjcard.2018.08.041 |
| Rights: |
info:eu-repo/semantics/closedAccess |
| Accession Number: |
edsbas.24CBD6C7 |
| Database: |
BASE |