| Title: |
Abstract P1160: Gut Microbiota, Circulating Inflammatory Markers, and Cardiac Dysfunction In Women Living With HIV |
| Authors: |
Wang, Zheng; Shitole, Sanyog; Sharma, Anjali; Hanna, David; Peters-Samuelson, Brandilyn; Wang, Tao; Post, Wendy; Landay, Alan; weber, kathleen; French, Audrey; MERENSTEIN, DANIEL; Haberlen, Sabina; Hinderliter, Alan; Ofotokun, Igho; Martinez, Claudia; Schexnayder, Julie; Lazar, Jason; Gustafson, Deborah; Anastos, Kathryn; Knight, Rob; Kaplan, Robert; Burk, Robert; KIZER, JORGE; Qi, Qibin |
| Source: |
Circulation ; volume 151, issue Suppl_1 ; ISSN 0009-7322 1524-4539 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2025 |
| Description: |
Introduction: The relationships among gut microbial alterations, host inflammation, and cardiac dysfunction remain understudied, particularly in the context of HIV. Hypothesis: We hypothesized that higher abundance of pro-inflammatory gut bacteria is associated with higher levels of host circulating inflammatory makers and cardiac dysfunction. Methods: We examined associations of gut microbial features (16S rRNA sequencing) with cardiac dysfunction (Echocardiography) in 973 women from the MACS/WIHS Combined Cohort Study. Cardiac dysfunction was defined as the presence of left ventricular systolic (LV ejection fraction |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1161/cir.151.suppl_1.p1160 |
| Availability: |
https://doi.org/10.1161/cir.151.suppl_1.p1160 |
| Accession Number: |
edsbas.257F3697 |
| Database: |
BASE |