| Description: |
Ruxandra Laza,1 Anca Lustrea,2 Elena Voichita Lazureanu,1 Cristian Iulian Oancea,3,4 Liana Dehelean,5 Emanuel Ionut Poplicean,3,6 Alina DoruÈ›a Bătrîn,7 Radu Stefan Romosan,5 Ana-Maria Romosan5 1Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, Romania; 2Department of Educational Sciences, University Clinic of Therapies and Psycho-Pedagogical Counseling, West University of Timisoara, Timisoara, Romania; 3Center for Research and Innovation in Precision Medicine of Respiratory Diseases, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, Romania; 4First Pulmonology Clinic, Clinical Hospital of Infectious Diseases and Pulmonology, Victor Babes, Timisoara, Romania; 5Department of Neurosciences-Psychiatry, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, Romania; 6Doctoral School, Faculty of General Medicine, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, Romania; 7Center for Translational Research and Systems Medicine, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, RomaniaCorrespondence: Anca Lustrea, Department of Educational Sciences, University Clinic of Therapies and Psycho-Pedagogical Counseling, West University of Timisoara, Timisoara, Romania, Email anca.lustrea@e-uvt.roPurpose: Psychosocial adaptation to chronic disease plays a central role in determining quality of life. Yet the mechanisms linking clinical factors to adaptation remain insufficiently understood, especially in Eastern European contexts and across different chronic conditions. This study tested whether self-efficacy mediates the relationship between comorbidities and number of medications on adaptation to chronic disease (as indicators of clinical burden and treatment complexity) and examined perceived social support and resilience as alternative mediators.Patients and Methods: Participants were 263 adults with chronic diseases recruited from public hospitals in ... |