Extracorporeal membrane oxygenation for respiratory failure related to Covid-19: A nationwide cohort study
| Title: | Extracorporeal membrane oxygenation for respiratory failure related to Covid-19: A nationwide cohort study |
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| Authors: | Nesseler N.; Fadel G.; Mansour A.; Para M.; Falcoz P. -E.; Mongardon N.; Porto A.; Bertier A.; Levy B.; Cadoz C.; Guinot P. -G.; Fouquet O.; Fellahi J. -L.; Ouattara A.; Guihaire J.; Ruggieri V. -G.; Gaudard P.; Labaste F.; Clavier T.; Brini K.; Allou N.; Lacroix C.; Chommeloux J.; Lebreton G.; Matthay M. A.; Provenchere S.; Flecher E.; Vincentelli A.; Pierrot M.; Chocron S.; Flicoteaux G.; Mauriat P.; Roze H.; Huet O.; Fischer M. -O.; Alessandri C.; Bellaiche R.; Constant O.; de Roux Q.; Ly A.; Mefert A.; Merle J. -C.; Picard L.; Skripkina E.; Folliguet T.; Fiore A.; d'Ostrevy N.; Morgan M. -C.; Nguyen M.; Gaide-Chevronnay L.; Terzi N.; Colin G.; Fabre O.; Astaneh A.; Issard J.; Fadel E.; Fabre D.; Girault A.; Ion I.; Menager J. B.; Mitilian D.; Mercier O.; Stephan F.; Thes J.; Jouan J.; Duburcq T.; Loobuyck V.; Manganiello S.; Moussa M.; Mugnier A.; Rousse N.; Desebbe O.; Henaine R.; Pozzi M.; Richard J. -C.; Riad Z.; Guervilly C.; Hraiech S.; Papazian L.; Castanier M.; Chanavaz C.; Gette S.; Louis G.; Portocarrero E.; Bischof N.; Kimmoun A.; Mattei M.; Perez P.; Bourdiol A.; Hourmant Y.; Mahe P. -J.; Rozec B.; Vourc'h M.; Aubert S.; Bazalgette F.; Roger C.; Jaquet P.; Lortat-Jacob B.; Mordant P.; Nataf P.; Patrier J.; Roue M.; Sonneville R.; Tran-Dinh A.; Wicky P. -H.; Al Zreibi C.; Cholley B.; Guyonvarch Y.; Hamada S.; Barbanti C.; Harrois A.; Matiello J.; Kerforne T.; Brechot N.; Combes A.; Constantin J. M.; D'Alessandro C.; Demondion P.; Demoule A.; Dres M.; Fartoukh M.; Hekimian G.; Juvin C.; Leprince P.; Levy D.; Luyt C. E.; de Chambrun M. P.; Schmidt M.; Schoell T.; Fillatre P.; Massart N.; Nicolas R.; Jonas M.; Vidal C.; Muccio S.; Di Perna D.; Mourvillier B.; Anselmi A.; Bounader K.; Esvan M.; Fougerou-Leurent C.; Launey Y.; Lebouvier T.; Parasido A.; Reizine F.; Seguin P.; Besnier E.; Carpentier D.; Olland A.; Villard M.; Bounes F.; Minville V.; Guillon A.; Fedun Y.; Ross J. T. |
| Contributors: | Nesseler, N.; Fadel, G.; Mansour, A.; Para, M.; Falcoz, P. -E.; Mongardon, N.; Porto, A.; Bertier, A.; Levy, B.; Cadoz, C.; Guinot, P. -G.; Fouquet, O.; Fellahi, J. -L.; Ouattara, A.; Guihaire, J.; Ruggieri, V. -G.; Gaudard, P.; Labaste, F.; Clavier, T.; Brini, K.; Allou, N.; Lacroix, C.; Chommeloux, J.; Lebreton, G.; Matthay, M. A.; Provenchere, S.; Flecher, E.; Vincentelli, A.; Pierrot, M.; Chocron, S.; Flicoteaux, G.; Mauriat, P.; Roze, H.; Huet, O.; Fischer, M. -O.; Alessandri, C.; Bellaiche, R.; Constant, O.; de Roux, Q.; Ly, A.; Mefert, A.; Merle, J. -C.; Picard, L.; Skripkina, E.; Folliguet, T.; Fiore, A.; D'Ostrevy, N.; Morgan, M. -C.; Nguyen, M.; Gaide-Chevronnay, L.; Terzi, N.; Colin, G.; Fabre, O.; Astaneh, A.; Issard, J.; Fadel, E.; Fabre, D.; Girault, A.; Ion, I.; Menager, J. B.; Mitilian, D.; Mercier, O.; Stephan, F.; Thes, J.; Jouan, J.; Duburcq, T.; Loobuyck, V.; Manganiello, S.; Moussa, M.; Mugnier, A.; Rousse, N.; Desebbe, O.; Henaine, R.; Pozzi, M.; Richard, J. -C.; Riad, Z.; Guervilly, C.; Hraiech, S.; Papazian, L.; Castanier, M.; Chanavaz, C.; Gette, S.; Louis, G.; Portocarrero, E.; Bischof, N.; Kimmoun, A.; Mattei, M.; Perez, P.; Bourdiol, A.; Hourmant, Y.; Mahe, P. -J.; Rozec, B.; Vourc'H, M.; Aubert, S.; Bazalgette, F.; Roger, C.; Jaquet, P.; Lortat-Jacob, B.; Mordant, P.; Nataf, P. |
| Publisher Information: | Lippincott Williams and Wilkins; TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA |
| Publication Year: | 2022 |
| Collection: | Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: | Cohort Studie; Human; Male; Pandemic; Retrospective Studie; COVID-19; Extracorporeal Membrane Oxygenation; Respiratory Insufficiency |
| Description: | Background: Despite expanding use, knowledge on extracorporeal membrane oxygenation support during the COVID-19 pandemic remains limited. The objective was to report characteristics, management, and outcomes of patients receiving extracorporeal membrane oxygenation with a diagnosis of COVID-19 in France and to identify pre-extracorporeal membrane oxygenation factors associated with in-hospital mortality. A hypothesis of similar mortality rates and risk factors for COVID-19 and non–COVID-19 patients on venovenous extracorporeal membrane oxygenation was made. Methods: The Extracorporeal Membrane Oxygenation for Respiratory Failure and/or Heart failure related to Severe Acute Respiratory Syndrome-Coronavirus 2 (ECMOSARS) registry included COVID-19 patients supported by extracorporeal membrane oxygenation in France. This study analyzed patients included in this registry up to October 25, 2020, and supported by venovenous extracorporeal membrane oxygenation for respiratory failure with a minimum follow-up of 28 days after cannulation. The primary outcome was in-hospital mortality. Risk factors for in-hospital mortality were analyzed. results: Among 494 extracorporeal membrane oxygenation patients included in the registry, 429 were initially supported by venovenous extracorporeal membrane oxygenation and followed for at least 28 days. The median (interquartile range) age was 54 yr (46 to 60 yr), and 338 of 429 (79%) were men. Management before extracorporeal membrane oxygenation cannulation included prone positioning for 411 of 429 (96%), neuromuscular blockage for 419 of 427 (98%), and NO for 161 of 401 (40%). A total of 192 of 429 (45%) patients were cannulated by a mobile extracorporeal membrane oxygenation unit. In-hospital mortality was 219 of 429 (51%), with a median follow-up of 49 days (33 to 70 days). Among pre-extracorporeal membrane oxygenation modifiable exposure variables, neuromuscular blockage use (hazard ratio, 0.286; 95% CI, 0.101 to 0.81) and duration of ventilation (more than 7 days compared to less ... |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/35348610; info:eu-repo/semantics/altIdentifier/wos/WOS:000781367400015; volume:136; issue:5; firstpage:732; lastpage:748; numberofpages:17; journal:ANESTHESIOLOGY; http://hdl.handle.net/11573/1655363 |
| DOI: | 10.1097/ALN.0000000000004168 |
| Availability: | http://hdl.handle.net/11573/1655363; https://doi.org/10.1097/ALN.0000000000004168 |
| Accession Number: | edsbas.26FE171A |
| Database: | BASE |