| Title: |
Balanced plasmonic-augmented silicon photonic interferometric sensor for biosensing applications |
| Authors: |
Elrabiaay, Mahmoud, A; Eleftheriou, Christia; Tsekenis, George; Bhalerao, Omkar; Suckow, Stephan; Lemme, Max; Das, Pratyusha; Markey, Laurent; Manolis, Athanasios; Tsiokos, Dimitris |
| Contributors: |
AMO Gesell Angew Mikro & Optoelekt GmbH; RWTH Aachen University = Rheinisch-Westfälische Technische Hochschule Aachen (RWTH Aachen); Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB); Université de Technologie de Belfort-Montbeliard (UTBM)-Centre National de la Recherche Scientifique (CNRS)-Université Bourgogne Europe (UBE) |
| Source: |
ISSN: 1094-4087 ; Optics Express ; https://hal.science/hal-05229750 ; Optics Express, 2025, 33 (11), pp.23110. ⟨10.1364/OE.533570⟩. |
| Publisher Information: |
CCSD; Optical Society of America - OSA Publishing |
| Publication Year: |
2025 |
| Collection: |
Université de Bourgogne (UB): HAL |
| Subject Terms: |
[PHYS]Physics [physics] |
| Description: |
International audience ; We demonstrate a self-referenced plasmonic augmented photonic Mach-Zehnder interferometer (MZI) for biosensing applications, incorporating a 70 µm long aluminum plasmonic waveguide in both arms of a silicon nitride (Si 3 N 4 ) MZI. Experimental results matched well with numerical simulations, showing extinction ratio (ER) values that exceed 55 dB and bulk sensitivity of 2322 nm/RIU. Wavelength stability measurements revealed 5×10 −3 nm thermal dependance for an ambient temperature fluctuation of 1-degree Celsius which is 50 times better than a conventional hybrid plasmo-photonic asymmetric MZI (aMZI) configuration, highlighting the robustness of the proposed balanced sensor scheme to ambient temperature fluctuations. Moreover, the experimental results show that the proposed sensor has a limit of detection up to 2.6 ×10 −6 RIU. Surface sensitivity of the proposed sensing transducer was evaluated through a C-reactive protein (CRP) surface saturation measurements and found equal to 10.45 nm/RIU for protein binding. Our validated simulation model was then benchmarked against a diverse set of target bio-analytes (proteins, viruses, bacteria, fungi) with surface sensitivity values reaching up to 2306 nm/RIU, indicating the sensor's heterogeneous detection capabilities. The presented self-referencing sensor configuration offers a cost-effective yet scalable and highly sensitive approach for multiplexed on-chip detection of diverse target analytes. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1364/OE.533570 |
| Availability: |
https://hal.science/hal-05229750; https://hal.science/hal-05229750v1/document; https://hal.science/hal-05229750v1/file/Mahmoud%20A.%20Elrabiaay%202025%20Balanced%20plasmonic-augmented%20silicon%20photonic%20interferometric%20sensor%20for%20biosensing%20applications.pdf; https://doi.org/10.1364/OE.533570 |
| Rights: |
http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.278F223C |
| Database: |
BASE |