| Title: |
Modified model for end stage liver disease score accurately predicts death or liver transplantation in acute flares of chronic hepatitis B |
| Authors: |
Fung, J; Lam, F; Chok, KSH; Seto, WK; Wong, T; Chan, A; Chan, SC; Lai, CL; Lo, CM; Yuen, MF |
| Publisher Information: |
//www.elsevier.com/locate/jhep; The Netherlands |
| Publication Year: |
2015 |
| Collection: |
University of Hong Kong: HKU Scholars Hub |
| Subject Terms: |
Medical sciences; Gastroenterology |
| Description: |
BACKGROUND AND AIMS: For patients chronically infected with hepatitis B virus, acute flares of chronic hepatitis B (AFOCHB) can be severe and fatal. The decision on whether to transplant or not is often a difficult one. The current study aims to determine the predictive value of short-term outcomes using the MELD score and its modified counterpart in AFOCHB patients. METHODS: Patients admitted with AFOCHB with ALT >5× upper limit of normal and HBVDNA of at least 4 logs IU/mL were included. Laboratory data was collected at the time of admission, at day 7, and at day 14. The MELD-ALT-Platelet (MAP) score was derived by additional points to the MELD score according to the ALT level (+1, +2, and +4 points for ALT ≤2000, 2000–3000, and >3000 respectively) and platelet level (+1, +2, +3, and +7 points for platelets ≥150, 100 to |
| Document Type: |
conference object |
| Language: |
English |
| Relation: |
Journal of Hepatology; S537, abstract no. P0590; 248019; WOS:000362830600307; suppl. 2; https://hub.hku.hk/handle/10722/214868; 62 |
| DOI: |
10.1016/S0168-8278(15)30796-0 |
| Availability: |
https://hub.hku.hk/handle/10722/214868; https://doi.org/10.1016/S0168-8278(15)30796-0 |
| Accession Number: |
edsbas.27BAAC8B |
| Database: |
BASE |