| Title: |
POCD HEART-BRAIN COMPLICATIONS: A NEUROPSYCHOLOGICAL AND PSYCHOLOGICAL OUTCOMES FOLLOWING CARDIO-SURGERY PRIN 2022 (cod. 2022PEK8YY) |
| Authors: |
Tropea A.; Tessari G.; Marcolongo F.; Guariglia C.; Giannini A. M.; Pecchinenda A.; Volterrani M. |
| Contributors: |
Tropea, A.; Tessari, G.; Marcolongo, F.; Guariglia, C.; Giannini, A. M.; Pecchinenda, A.; Volterrani, M. |
| Publication Year: |
2025 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
Postoperative Cognitive Dysfunction (POCD); Cardiac Surgery; Neuropsychological Assessment |
| Description: |
Background. Postoperative Cognitive Dysfunction (POCD) affects approximately 50-67% of patients shortly after cardiac surgery. POCD is characterized by impairments in memory, executive functioning, attention, information processing, language, and perceptual-motor abilities (Vedel et al., 2019). Its etiology is multifactorial, involving cerebral emboli, hypoperfusion, and inflammation. Early detection through neuropsychological assessment is crucial but still under-researched (Glumac et al., 2021). The Enhanced Recovery After Surgery (ERAS) guidelines (Evered et al., 2018) recommend applying diagnostic tools used in neurocognitive disorder research to detect postoperative cognitive changes. Aims. This project aimed to design and implement a neuropsychological assessment for early POCD detection following cardiac surgery. Materials and methods. A neuropsychological protocol was developed and administered to 45 cardiac surgery patients (36 males, 9 females; mean age = 59.5; SD = 12; mean education = 17 years; SD = 5.6), recruited from IRCCS "San Raffaele" in Rome. Using SPSS software, we conducted descriptive statistics to profile cognitive performance and correlation analyses to identify connections with clinical data. Moreover, a Severity Index (SI) was created based on three factors commonly cited in the literature: number of heart bypasses, presence of hypertension, and time since surgery. Additional correlations examined links between psychological symptoms and neuropsychological outcomes. Results. Patients showed the worst performance in the Digit Span Forward (82.2% impaired) and Digit Span Backward (75.6%) tests. The SI did not correlate with any neuropsychological and emotional (DASS-21) score. However, performance on the Symbol Digit Modalities Test was significantly associated with hypertension (p = 0.033), and performance on the Clock Drawing Test was linked to valve type (p = 0.007). Reyâ€TMs Immediate Recall scores were negatively associated with DASS-21 depression scores (p = 0.022) and positively ... |
| Document Type: |
conference object |
| Language: |
English |
| Relation: |
ispartofbook:Book of abstracts 55° CONGRESSO SIN PADOVA 2025; 55° CONGRESSO SIN PADOVA 2025; https://hdl.handle.net/11573/1750471 |
| Availability: |
https://hdl.handle.net/11573/1750471 |
| Accession Number: |
edsbas.28267265 |
| Database: |
BASE |