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Functional impact of long COVID among healthcare workers with comorbidities in Quebec, Canada: a cross-sectional study

Title: Functional impact of long COVID among healthcare workers with comorbidities in Quebec, Canada: a cross-sectional study
Authors: Isangwe, Sabine; Talbot, Denis; Coutu, Marie-France; Canitrot, Elisabeth; Décary, Simon; Falcone, Emilia Liana; Ouakki, Manale; Latouche, Philippe; Piché, Alain; Simard, Marc; Balem, Marianne; De Serres, Gaston; Carazo, Sara
Contributors: Fonds de Recherche du Québec - Santé; Ministère de la Santé et des Services sociaux du Québec
Source: BMJ Public Health ; volume 4, issue 1, page e004108 ; ISSN 2753-4294
Publisher Information: BMJ
Publication Year: 2026
Description: Introduction Long COVID is a frequent post-infectious chronic condition that impacts quality of life and work performance. Whether individuals with comorbidities experience a greater functional impact of long COVID is unknown. We evaluated the functional impact of long COVID among healthcare workers (HCWs) with chronic cardiovascular diseases, chronic respiratory diseases, obesity or a history of depression, and compared it with that of HCWs without comorbidities. Methods We conducted a cross-sectional study in Quebec, Canada. We compared self-reported long COVID cases to COVID-19-infected controls without long COVID on work ability, work functioning, health-related absenteeism, dyspnoea-associated impairment and psychological distress among HCWs (a) with at least one of the four comorbidities, (b) with each of the four comorbidities and (c) without comorbidities. We used inverse probability of exposure and robust Poisson regressions to estimate adjusted prevalence differences (aPD) and prevalence ratios. Comorbidity data were obtained from the Quebec integrated chronic disease surveillance system. Results A total of 3754 and 8439 HCWs with and without comorbidities, respectively, were included. Among HCWs with at least one of the four comorbidities, long COVID was associated with higher prevalence of low work ability (aPD=15%, 95% CI: 12% to 18%), low work functioning (aPD=27%, 95% CI: 22% to 31%), health-related long-term absenteeism (aPD=8%, 95% CI: 5% to 11%), dyspnoea-associated impairment (aPD=23%, 95% CI: 19% to 26%) and psychological distress (aPD=24%, 95% CI: 20% to 28%). aPDs were greater among HCWs with comorbidities than among those without for low work ability (p=0.013 for interaction), for low work functioning (p=0.034) and for dyspnoea-associated impairment (p
Document Type: article in journal/newspaper
Language: English
DOI: 10.1136/bmjph-2025-004108
Availability: https://doi.org/10.1136/bmjph-2025-004108; https://syndication.highwire.org/content/doi/10.1136/bmjph-2025-004108
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.285A6526
Database: BASE