| Title: |
Associations Between End-Tidal Carbon Dioxide During Pediatric Cardiopulmonary Resuscitation, Cardiopulmonary Resuscitation Quality, and Survival |
| Authors: |
Morgan, Ryan W.; Reeder, Ron W.; Bender, Dieter; Cooper, Kellimarie K.; Friess, Stuart H.; Graham, Kathryn; Meert, Kathleen L.; Mourani, Peter M.; Murray, Robert; Nadkarni, Vinay M.; Nataraj, Chandrasekhar; Palmer, Chella A.; Srivastava, Neeraj; Tilford, Bradley; Wolfe, Heather A.; Yates, Andrew R.; Berg, Robert A.; Sutton, Robert M.; Ahmed, Tageldin; Bell, Michael J.; Bishop, Robert; Bochkoris, Matthew; Burns, Candice; Carpenter, Todd C.; Carcillo, Joseph A.; Dean, J. Michael; Diddle, J. Wesley; Federman, Myke; Fernandez, Richard; Fink, Ericka L; Franzon, Deborah; Frazier, Aisha H.; Hall, Mark; Hehir, David A.; Horvat, Christopher M.; Huard, Leanna L.; Maa, Tensing; Manga, Arushi; McQuillen, Patrick S.; Naim, Maryam Y.; Notterman, Daniel; Pollack, Murray M.; Sapru, Anil; Schneiter, Carleen; Sharron, Matthew P.; Tabbutt, Sarah; Viteri, Shirley; Wessel, David; Zuppa, Athena F. |
| Contributors: |
HHS | NIH | National Heart, Lung, and Blood Institute; HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development |
| Source: |
Circulation ; volume 149, issue 5, page 367-378 ; ISSN 0009-7322 1524-4539 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2024 |
| Description: |
BACKGROUND: Supported by laboratory and clinical investigations of adult cardiopulmonary arrest, resuscitation guidelines recommend monitoring end-tidal carbon dioxide ( ETCO 2 ) as an indicator of cardiopulmonary resuscitation (CPR) quality, but they note that “specific values to guide therapy have not been established in children.” METHODS: This prospective observational cohort study was a National Heart, Lung, and Blood Institute–funded ancillary study of children in the ICU-RESUS trial (Intensive Care Unit-Resuscitation Project; NCT02837497). Hospitalized children (≤18 years of age and ≥37 weeks postgestational age) who received chest compressions of any duration for cardiopulmonary arrest, had an endotracheal or tracheostomy tube at the start of CPR, and evaluable intra-arrest ETCO 2 data were included. The primary exposure was event-level average ETCO 2 during the first 10 minutes of CPR (dichotomized as ≥20 mm Hg versus |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1161/circulationaha.123.066659 |
| DOI: |
10.1161/CIRCULATIONAHA.123.066659 |
| Availability: |
https://doi.org/10.1161/circulationaha.123.066659; https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.123.066659 |
| Accession Number: |
edsbas.287A12D7 |
| Database: |
BASE |