| Title: |
From One Cancer to Two ; [¹⁸F]FES PET/CT Redirected Diagnosis and Therapy in a Metastatic Breast Cancer Patient |
| Authors: |
Dupont, Anne-Claire; Farges, Mathieu; Chapelle, Benoit; Cancel, Mathilde; Ribeiro, Maria-Joao Santiago |
| Source: |
Clinical Nuclear Medicine ; volume 51, issue 5, page 419-420 ; ISSN 0363-9762 1536-0229 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2026 |
| Description: |
A 59-year-old woman with an ulcerated right breast lesion was diagnosed with ER-positive invasive ductal carcinoma. Staging [¹⁸F]FDG PET/CT revealed intense uptake in the breast, axillary nodes, a large hypermetabolic pulmonary mass, mediastinal lymphadenopathies, and bone lesions. Because of this metabolic pattern, [¹⁸F]FES PET/CT was performed, demonstrating [¹⁸F]FES-avid bone metastases but no uptake in the lung mass. Biopsy confirmed a BRAF V600E-mutated lung adenocarcinoma. [¹⁸F]FES PET/CT proved crucial in differentiating synchronous primary malignancies from metastatic spread and guiding targeted therapy with dabrafenib-trametinib. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1097/rlu.0000000000006386 |
| DOI: |
10.1097/RLU.0000000000006386 |
| Availability: |
https://doi.org/10.1097/rlu.0000000000006386; https://journals.lww.com/10.1097/RLU.0000000000006386 |
| Rights: |
http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.29564C3F |
| Database: |
BASE |