| Title: |
Microsatellite allele imputation from SNP genotypes for parentage verification in sport horses |
| Authors: |
Crichan, H; Engler, C; Goulas, E; Dhorne-Pollet, S; Addes, M; Ricard, Anne |
| Contributors: |
Pôle développement innovation et recherche Arnac-Pompadour; Institut Français du Cheval et de l'équitation Arnac-Pompadour (IFCE); Génétique Animale et Biologie Intégrative (GABI); AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) |
| Source: |
World Congress on Genetics Applied to Livestock Production ; https://hal.inrae.fr/hal-04650364 ; World Congress on Genetics Applied to Livestock Production, Jul 2022, Rotterdam (NL), Netherlands ; https://eaap.org/event/wcgalp-2022-world-congress-on-genetics-applied-to-livestock-production-rotterdam-the-netherlands/ |
| Publisher Information: |
CCSD |
| Publication Year: |
2022 |
| Subject Terms: |
[SDV]Life Sciences [q-bio] |
| Subject Geographic: |
Rotterdam (NL); Netherlands |
| Description: |
International audience ; In the major livestock species, parentage verification is done using Single Nucleotide Polymorphism (SNP) markers. ISAG is working to produce a SNP panel for parental verification in horses. There will be a transition period between microsatellites (MS) and SNPs. Without any tool for the transition, breeders will have to double genotype foals or re-genotype mares and stallions with SNPs. We wanted to produce a tool to predict MS genotypes using SNP markers that could be included on a chip with the new ISAG panel. To achieve this we built a correspondence table between MS alleles and SNP haplotypes. We validated it using kfold cross-validation. With the highest SNP density, we obtained 3.4% of incompatibilities over 2 or more MS or 96.6% of parental verification achieved over the major breeds in our study, Selle-Français (SF, 54%), French Trotters (TF, 22%), Arabs (AR, 17%), Anglo-Arabs (AA, 3%) and other saddlebreds (SE, 4%). |
| Document Type: |
conference object |
| Language: |
English |
| Availability: |
https://hal.inrae.fr/hal-04650364; https://hal.inrae.fr/hal-04650364v1/document; https://hal.inrae.fr/hal-04650364v1/file/Circhan_WCGALP.pdf |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.298CE0B3 |
| Database: |
BASE |