| Title: |
Blood pressure variability: a review |
| Authors: |
Kulkarni S.; Parati G.; Bangalore S.; Bilo G.; Kim B. J.; Kario K.; Messerli F.; Stergiou G.; Wang J.; Whiteley W.; Wilkinson I.; Sever P. S. |
| Contributors: |
Kulkarni, S; Parati, G; Bangalore, S; Bilo, G; Kim, B; Kario, K; Messerli, F; Stergiou, G; Wang, J; Whiteley, W; Wilkinson, I; Sever, P |
| Publisher Information: |
Lippincott Williams and Wilkins; US |
| Publication Year: |
2025 |
| Collection: |
Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| Subject Terms: |
ASCOT study; blood pressure variability; coronary event; stroke; MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE; Settore MEDS-07/B - Malattie dell'apparato cardiovascolare |
| Description: |
Blood pressure variability (BPV) predicts cardiovascular events independent of mean blood pressure. BPV is defined as short-term (24-h), medium or long- term (weeks, months or years). Standard deviation, coefficient of variation and variation independent of the mean have been used to quantify BPV. High BPV is associated with increasing age, diabetes, smoking and vascular disease and is a consequence of premature ageing of the vasculature. Long-term BPV has been incorporated into cardiovascular risk models (QRISK) and elevated BPV confers an increased risk of cardiovascular outcomes even in subjects with controlled blood pressure. Long-acting dihydropyridine calcium channel blockers and thiazide diuretics are the only drugs that reduce BPV and for the former explains their beneficial effects on cardiovascular outcomes. We believe that BPV should be incorporated into blood pressure management guidelines and based on current evidence, long-acting dihydropyridines should be preferred drugs in subjects with elevated BPV. |
| Document Type: |
article in journal/newspaper |
| File Description: |
STAMPA |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40084481; info:eu-repo/semantics/altIdentifier/wos/WOS:001488654300003; volume:43; issue:6; firstpage:929; lastpage:938; numberofpages:10; journal:JOURNAL OF HYPERTENSION; https://hdl.handle.net/10281/551621 |
| DOI: |
10.1097/HJH.0000000000003994 |
| Availability: |
https://hdl.handle.net/10281/551621; https://doi.org/10.1097/HJH.0000000000003994 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.29F7C5FF |
| Database: |
BASE |