| Title: |
High early mortality following percutaneous nephrostomy in metastatic cancer: a national analysis of outcomes |
| Authors: |
Dosanjh, Amandeep; Coupland, Benjamin; Mytton, Jemma; King, Dominic Stephen; Mintz, Harriet; Lock, Anna; Nanton, Veronica; Mariappan, Param; Trudgill, Nigel; Patel, Prashant |
| Source: |
BMJ Supportive & Palliative Care ; volume 14, issue e2, page e2100-e2109 ; ISSN 2045-435X 2045-4368 |
| Publisher Information: |
BMJ |
| Publication Year: |
2024 |
| Description: |
Objectives To assess the outcomes of percutaneous nephrostomy in England for renal decompression, in the context of metastatic cancer. Methods Retrospective observational study of all patients undergoing nephrostomy with a diagnosis of metastatic cancer from 2010 to 2019 in England, identified and followed up within Hospital Episode Statistics. The primary outcome measure was mortality (14-day and 30-day postprocedure). Secondary outcomes included subsequent chemotherapy or surgery and direct complications of nephrostomy. Results 10 932 patients were identified: 58.0% were male, 51.0% were >70 years old and 57.7% had no relevant comorbidities (according to Charlson’s criteria, other than cancer). 1 in 15 patients died within 14 days of nephrostomy and 1 in 6 died within 30 days. Factors associated with higher 30-day mortality were the presence of comorbidities (Charlson score 1–4 (OR 1.27, 95% CI 1.08 to 1.50, p=0.003), score 5+ (OR 1.29, 95% CI 1.14 to 1.45), p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1136/spcare-2024-004937 |
| Availability: |
https://doi.org/10.1136/spcare-2024-004937; https://syndication.highwire.org/content/doi/10.1136/spcare-2024-004937 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.29FBEC4 |
| Database: |
BASE |