| Title: |
Oncology-led early identification of nutritional risk: a pragmatic, evidence-based protocol (PRONTO) |
| Authors: |
Muscaritoli M.; Bar-Sela G.; Battisti N. M. L.; Belev B.; Contreras-Martinez J.; Cortesi E.; de Brito-Ashurst I.; Prado C. M.; Ravasco P.; Yalcin S. |
| Contributors: |
Muscaritoli, M.; Bar-Sela, G.; Battisti, N. M. L.; Belev, B.; Contreras-Martinez, J.; Cortesi, E.; de Brito-Ashurst, I.; Prado, C. M.; Ravasco, P.; Yalcin, S. |
| Publisher Information: |
MDPI AG; Basel, 4052 Svizzera |
| Publication Year: |
2023 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
PRONTO; antineoplastic therapy; cachexia; cancer; malnutrition; mobility; nutrition; protocol; risk identification; sarcopenia; strength |
| Description: |
Simple Summary Early identification of patients on antineoplastic therapy who are at risk for or already malnourished is critical for optimizing treatment success. Malnourished patients are at increased risk for being unable to tolerate the most effective 'level' and 'duration' of treatment, with grave implications for both the short- (during treatment) and long-term outcomes. Herein, we provide a practical PROtocol for NuTritional risk in Oncology (PRONTO) to enable oncologists to identify patients with or at risk of malnutrition for further evaluation and follow-up with members of the multidisciplinary care team (MDT). Additional guidance is included on the oncologist-led provision of nutritional support if referral to a dietary service is not available. Nutritional issues, including malnutrition, low muscle mass, sarcopenia (i.e., low muscle mass and strength), and cachexia (i.e., weight loss characterized by a continuous decline in skeletal muscle mass, with or without fat loss), are commonly experienced by patients with cancer at all stages of disease. Cancer cachexia may be associated with poor nutritional status and can compromise a patient's ability to tolerate antineoplastic therapy, increase the likelihood of post-surgical complications, and impact long-term outcomes including survival, quality of life, and function. One of the primary nutritional problems these patients experience is malnutrition, of which muscle depletion represents a clinically relevant feature. There have been recent calls for nutritional screening, assessment, treatment, and monitoring as a consistent component of care for all patients diagnosed with cancer. To achieve this, there is a need for a standardized approach to enable oncologists to identify patients commencing and undergoing antineoplastic therapy who are or who may be at risk of malnutrition and/or muscle depletion. This approach should not replace existing tools used in the dietitian's role, but rather give the oncologist a simple nutritional protocol for optimization ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/36672329; info:eu-repo/semantics/altIdentifier/wos/WOS:000916998200001; volume:15; issue:2; numberofpages:14; journal:CANCERS; https://hdl.handle.net/11573/1676727 |
| DOI: |
10.3390/cancers15020380 |
| Availability: |
https://hdl.handle.net/11573/1676727; https://doi.org/10.3390/cancers15020380 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.2A834255 |
| Database: |
BASE |