Isoform-Specific Upregulation of Palladin in Human and Murine Pancreas Tumors
| Title: | Isoform-Specific Upregulation of Palladin in Human and Murine Pancreas Tumors |
|---|---|
| Authors: | Silvia M. Goicoechea; Brian Bednarski; Christianna Stack; David W. Cowan; Keith Volmar; Edna Cukierman; Anil K. Rustgi; Teresa Brentnall; Rosa F. Hwang; Christopher A. G; Carol A. Otey |
| Contributors: | The Pennsylvania State University CiteSeerX Archives |
| Source: | ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/df/d2/PLoS_One_2010_Apr_26_5(4)_e10347.tar.gz |
| Collection: | CiteSeerX |
| Description: | Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with a characteristic pattern of early metastasis, which is driving a search for biomarkers that can be used to detect the cancer at an early stage. Recently, the actin-associated protein palladin was identified as a candidate biomarker when it was shown that palladin is mutated in a rare inherited form of PDA, and overexpressed in many sporadic pancreas tumors and premalignant precursors. In this study, we analyzed the expression of palladin isoforms in murine and human PDA and explored palladin’s potential use in diagnosing PDA. We |
| Document Type: | text |
| File Description: | application/zip |
| Language: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.4297 |
| Availability: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.4297 |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| Accession Number: | edsbas.2B22EF67 |
| Database: | BASE |