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Infectious Complications in Laparoscopic Gynecologic Oncology Surgery within an ERAS-Compliant Setting

Title: Infectious Complications in Laparoscopic Gynecologic Oncology Surgery within an ERAS-Compliant Setting
Authors: Capozzi V. A.; De Finis A.; Scarpelli E.; Gallinelli A.; Monfardini L.; Cianci S.; Gulino F. A.; Rotondella I.; Celora G. M.; Martignon G.; Ghi T.; Berretta R.
Contributors: Capozzi, V. A.; De Finis, A.; Scarpelli, E.; Gallinelli, A.; Monfardini, L.; Cianci, S.; Gulino, F. A.; Rotondella, I.; Celora, G. M.; Martignon, G.; Ghi, T.; Berretta, R.
Publication Year: 2024
Collection: Università degli Studi di Messina: IRIS
Subject Terms: enhanced recovery after surgery (ERAS); gynecologic malignancie; gynecologic oncology; infectious complication; laparoscopic surgery; minimally invasive surgery (MIS); morbidity prevention; postoperative complications
Description: Minimally Invasive Surgery (MIS) represents a safe and feasible option for the surgical treatment of gynecologic malignancies, offering benefits, including reduced blood loss, lower complications, and faster recovery, without compromising oncological outcomes in selected patients. MIS is widely accepted in early-stage gynecologic malignancies, including endometrial cancer, cervical tumors measuring 2 cm or less, and early-stage ovarian cancer, considering the risk of surgical spillage. Despite its advantages, MIS does not rule out the possibility of adverse events such as postoperative infections. This retrospective study on 260 patients undergoing laparoscopic surgery at Parma University Hospital for gynecologic malignancies explores the incidence and risk factors of postoperative infectious complications. The Clavien-Dindo classification was used to rank postoperative surgical complications occurring 30 days after surgery and Enhanced Recovery After Surgery (ERAS) recommendations put into practice. In our population, 15 (5.8%) patients developed infectious complications, predominantly urinary tract infections (9, 3.5%). Longer surgical procedures were independently associated with higher postoperative infection risk (p = 0.045). Furthermore, C1 radical hysterectomy correlated significantly with infectious complications (p = 0.001, OR 3.977, 95% CI 1.370-11.544). In conclusion, compared to prior research, our study reported a lower rate of infectious complications occurrence and highlights the importance of adopting infection prevention measures.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/38392581; volume:14; issue:2; firstpage:748; lastpage:765; numberofpages:18; journal:JOURNAL OF PERSONALIZED MEDICINE; https://hdl.handle.net/11570/3296390
DOI: 10.3390/jpm14020147
Availability: https://hdl.handle.net/11570/3296390; https://doi.org/10.3390/jpm14020147
Accession Number: edsbas.2BAFAD2D
Database: BASE