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Diastereoselective Synthesis of Alkylcyclopropane-Annelated Methyl 2-Iminoimidazolidinecarboxylates

Title: Diastereoselective Synthesis of Alkylcyclopropane-Annelated Methyl 2-Iminoimidazolidinecarboxylates
Authors: Noetzel, Marcus W.; Frank, Daniel; Labahn, Thomas; Magull, Joerg; de Meijere, Armin
Contributors: Noetzel, Marcus W.; Frank, Daniel; Labahn, Thomas; Magull, Joerg; de Meijere, Armin
Publisher Information: Wiley-v C H Verlag Gmbh
Publication Year: 2009
Collection: Georg-August-Universität Göttingen: GoeScholar
Description: Cyclopropane- and alkylcyclopropane-annelated methyl imidazolidinecarboxylates 5 are formed from unsubstituted 1-H and from 2'-substituted methyl 2-chloro-2-cyclopropylideneacetates (1-R) and N,N',N ''-triarylguanidines (2) in a domino process consisting of a Michael addition and an immediately ensuing ring closure by intramolecular nucleophilic substitution in moderate to very good yields (30-95%, 8 examples). The products 5 with alkyl substituents on the spirocyclopropane moiety are formed diastereoselectively. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) ; Land Niedersachsen and BayerCrop-Science AG; BASF AG
Document Type: article in journal/newspaper
Language: unknown
Relation: 000265169700007
DOI: 10.1002/ejoc.200801205
Availability: https://resolver.sub.uni-goettingen.de/purl?gro-2/17033; https://doi.org/10.1002/ejoc.200801205
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.2C18E620
Database: BASE