| Title: |
Cardiogenic shock in the course of myocardial infarction: the results of the Shock-POL registry |
| Authors: |
Wybraniec, Maciej T; Sufryd, Artur; Cichoń, Małgorzata; Tokarek, Tomasz; Dykla, Dominika; Zeliaś, Aleksander; Holcman, Katarzyna; Szczepara, Sylwia; Kowalik, Robert; Fojt, Anna; Kapłon-Cieślicka, Agnieszka; Błaziak, Mikołaj; Sokolski, Mateusz; Tkaczyszyn, Michał; Kuliczkowski, Wiktor; Gąsior, Paweł; Pawlus, Paweł; Wojakowski, Wojciech; Morawiec, Beata; Kawecki, Damian; Kułach, Andrzej; Smolka, Grzegorz; Janas, Adam; Mizia-Stec, Katarzyna; Wita, Krystian |
| Source: |
ESC Heart Failure ; ISSN 2055-5822 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2026 |
| Description: |
Aims Cardiogenic shock (CS) represents an ominous complication of acute myocardial infarction (AMI) with mortality rate exceeding 50%. The aim of the study was to evaluate current management, outcomes and risk factors of mortality of AMI-related CS. Methods This snap-shot registry evaluated all patients with AMI-related CS hospitalized in 9 cardiology centers across Poland between January and December 2023. The inclusion criteria involved CS defined as prolonged (>20 min) hypotension with signs of peripheral hypoperfusion and diagnosis of AMI qualified for urgent coronary angiography. The primary endpoint was in-hospital mortality. Results The study comprised 141 patients (72.3% men; mean age was 69.2 [14] years). The majority of patients were in Society for Cardiovascular Angiography and Interventions class C (n=71,50.4%), followed by class D (n=46,32.6%) and class E (n=24,17.0%). Percutaneous coronary intervention was performed in 133 cases (94.3%) while coronary artery bypass graft in 5 (3.5%). Mechanical circulatory support (MCS) was used in 33 patients (23.4%) and involved intra-aortic balloon pump (n=26,18.4%), Impella CP (n=6,4.3%), Impella 5.5 (n=2,1.4%) and veno-arterial extracorporeal membrane oxygenation (n=10,7.1%). In-hospital mortality rate was 47.5% (n=67), while 30-day mortality was 51.8% (n=73). Cox proportional hazards model showed that non-ST-elevation AMI (HR=2.38,95%CI:1.19-4.75), lack of the need for antibiotic therapy (HR=2.61, 95%CI:1.26-5.39), elevated lactates (unit HR per 1 mmol/l=1.19, 95%CI:1.11-1.27) and age (unit HR=1.05; 95%CI:1.02-1.07) were independent predictors of in-hospital mortality. Conclusions Short-term mortality rate of AMI-related CS still amounts to 50%, which advocates in favor of further research evaluating the true role of MCS in this population. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/eschf/xvag066 |
| DOI: |
10.1093/eschf/xvag066/67138446/xvag066.pdf |
| Availability: |
https://doi.org/10.1093/eschf/xvag066; https://academic.oup.com/eschf/advance-article-pdf/doi/10.1093/eschf/xvag066/67138446/xvag066.pdf |
| Rights: |
https://creativecommons.org/licenses/by-nc/4.0/ |
| Accession Number: |
edsbas.2C8A35C1 |
| Database: |
BASE |