| Title: |
Interrupting sitting acutely attenuates cardiometabolic risk markers in South Asian adults living with overweight and obesity. |
| Authors: |
Dey, KC; Zakrzewski-Fruer, JK; Smith, LR; Jones, RL; Bailey, DP |
| Publication Year: |
2024 |
| Collection: |
Queen Mary University of London: Queen Mary Research Online (QMRO) |
| Subject Terms: |
Cardiometabolic health; Glucose; Metabolic load index; Obesity; Sedentary behaviour; South Asian; Adult; Humans; Overweight; Blood Glucose; Insulin; Cross-Over Studies; Walking; Postprandial Period; Cardiovascular Diseases |
| Description: |
PURPOSE: This study examined the acute effects of interrupting sitting with light-intensity walking on postprandial cardiometabolic risk markers in South Asian adults. METHODS: South Asians with overweight/obesity (n = 19; body mass index [BMI] > 23 kg·m-2) and normal-weight (n = 8; BMI 18.0-22.9 kg·m-2) aged 48.8 ± 5.6 years completed two, 5-h conditions: (1) prolonged sitting (SIT), and (2) interrupted sitting with 5-min bouts of light-intensity walking every 30-min (INT-SIT). Blood samples and resting expired air samples were collected throughout each condition. Statistical analyses were completed using linear mixed models. RESULTS: In participants with overweight/obesity, postprandial glucose, triglycerides (TAG) and metabolic load index (MLI) over time were lower, whereas resting substrate utilisation and resting energy expenditure (REE) were higher, in INT-SIT than SIT (all p ≤ 0.05). Compared with SIT (0.18 [95% CI 0.13, 0.22] kcal.min-1), INT-SIT (0.23 [95% CI 0.18, 0.27] kcal.min-1) increased postprandial REE iAUC in participants with overweight/obesity (p = 0.04, d = 0.51). Postprandial TAG concentrations over time were lower in INT-SIT versus SIT (p = 0.01, d = 30) in normal-weight participants, with no differences in any other outcomes for this sample group. CONCLUSION: These findings suggest that interrupting sitting with 5-min bouts of light walking every 30-min acutely attenuates cardiometabolic risk markers among South Asians living with overweight/obesity, whereas limited effects may be seen in individuals with normal-weight. |
| Document Type: |
article in journal/newspaper |
| File Description: |
1163 - 1174 |
| Language: |
English |
| Relation: |
Eur J Appl Physiol; https://qmro.qmul.ac.uk/xmlui/handle/123456789/99006 |
| DOI: |
10.1007/s00421-023-05345-7 |
| Availability: |
https://qmro.qmul.ac.uk/xmlui/handle/123456789/99006; https://doi.org/10.1007/s00421-023-05345-7 |
| Rights: |
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. ; © The Author(s) 2023 |
| Accession Number: |
edsbas.2CA00161 |
| Database: |
BASE |