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Integrating Bioenergetic Therapy Model with Neuropsychopharmacological Interventions in Long-standing Treatment-resistant Schizophrenia: Case Series and Review of Literature

Title: Integrating Bioenergetic Therapy Model with Neuropsychopharmacological Interventions in Long-standing Treatment-resistant Schizophrenia: Case Series and Review of Literature
Authors: Khairkar, Praveen; Chadha, Divya; Kamble, Ashwini; Khivsara, Archish; Modi, Rohan; Khairkar, Rajesh
Source: Annals of Neurosciences ; ISSN 0972-7531 0976-3260
Publisher Information: SAGE Publications
Publication Year: 2026
Description: Background The bioenergetic therapy model combines holistic somatic therapy with psychotherapy, addressing both physical and emotional aspects of healing. In cases of long-standing treatment-resistant schizophrenia (TRS), which may persist for over two decades, finding effective therapeutic strategies remain a significant challenge. Despite numerous treatment options, no existing reports integrate somatosensory therapy with neuropsychopharmacological interventions for these complex cases. Purpose To demonstrate the integration of bioenergetic therapy with neuropsychopharmacological interventions in managing long-standing treatment-resistant schizophrenic cases. Methods Two cases of long-standing schizophrenia were illustrated for how we integrated somatosensory bioenergetics principles with neuropsychopharmacology. They had emotional and/or physical abuse in addition to psychotic symptoms without any pre-morbid schizoid/paranoid traits or psychiatric history of substance abuse, and presented to us with complaints of high sensitivity to rejection, persecutory delusions, third-person auditory hallucinations, irritability, episodic aggression, psychomotor retardation, disturbed sleep, and declining professional performance. Results A systematic cognitive deficit evaluation, slow building of clozapine (100 mg/day), integration of somatosensory therapy, family system therapy model and cognitive enhancement therapy were integrated. This integration of somatosensory therapy with neuropsychopharmacological interventions led to a significant improvement over a four-week period. Notable recovery was observed in the experience of being touched for rebuilding maternal trust and developing a therapeutic rapport. Conclusion Integration of multiple system bioenergetic model in chronic TRS adds another novel way to its management which is an advanced extrapolation of the Bio-Psycho-Social model of schizophrenia. Bioenergetic analysis facilitated a unique somatic psychotherapy that combined cognitive feelings, somatic, and ...
Document Type: article in journal/newspaper
Language: English
DOI: 10.1177/09727531251409878
Availability: https://doi.org/10.1177/09727531251409878; https://journals.sagepub.com/doi/pdf/10.1177/09727531251409878; https://journals.sagepub.com/doi/full-xml/10.1177/09727531251409878
Rights: https://creativecommons.org/licenses/by-nc/4.0/ ; https://journals.sagepub.com/page/policies/text-and-data-mining-license
Accession Number: edsbas.2CE7A9E0
Database: BASE