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Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report

Title: Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report
Authors: Arslan, Deniz; Uysal, Mukremin; Tatli, Ali Murat; Gunduz, Seyda; Goksu, Sema Sezgin; Bassorgun, Cumhur Ibrahim; Coskun, Hasan Senol
Publisher Information: Hindawi Ltd
Publication Year: 2026
Collection: Afyon Kocatepe University Institutional Repository (DSpace@AKU)
Subject Terms: Metastases; Patterns
Description: Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way, to peripheral lymph nodes in lymphogenous way, and to peripheral tissues in adjacency way, yet bone marrow (BM) and cutaneous metastasis are quite seldom. Pancytopenia is a more frequent finding identified in BM metastasis of solid organ cancers, and isolated thrombocytopenia is less often. The human epidermal growth factor 2 (HER-2) is positive in gastric cancer at a rate of 7-34%. Here, we have presented our HER-2 positive gastric cancer incident which presented with BM and cutaneous metastasis, and has no 18F-fluoro-2-deoxi-D-glucose (FDG) involvement except bone metastases.
Document Type: article in journal/newspaper
Language: English
Relation: Case Reports in Oncological Medicine; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.1155/2014/194636; https://hdl.handle.net/11630/26733; 2014; WOS:000215601300012; N/A
DOI: 10.1155/2014/194636
Availability: https://hdl.handle.net/11630/26733; https://doi.org/10.1155/2014/194636
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.2CEE664F
Database: BASE