| Title: |
Phylogenetically related Argentinean and Australian Escherichia coli O157 isolates are distinguished by virulence clades and alternative shiga toxin 1 and 2 prophages |
| Authors: |
Mellor, GE; Sim, EM; Barlow, RS; D'Astek, BA; Galli, L; Chinen, I; Rivas, M; Gobius, KS |
| Publication Year: |
2012 |
| Collection: |
University of Technology Sydney: OPUS - Open Publications of UTS Scholars |
| Subject Terms: |
Microbiology; Escherichia coli O157; Coliphages; Prophages; Escherichia coli Infections; DNA; Bacterial; Virulence Factors; Sequence Analysis; Virulence; Molecular Sequence Data; Argentina; Australia; Shiga Toxin 1; Shiga Toxin 2 |
| Description: |
Shiga toxigenic Escherichia coli O157 is the leading cause of hemolytic uremic syndrome (HUS) worldwide. The frequencies of stx genotypes and the incidences of O157-related illness and HUS vary significantly between Argentina and Australia. Locusspecific polymorphism analysis revealed that lineage I/II (LI/II) E. coli O157 isolates were most prevalent in Argentina (90%) and Australia (88%). Argentinean LI/II isolates were shown to belong to clades 4 (28%) and 8 (72%), while Australian LI/II isolates were identified as clades 6 (15%), 7 (83%), and 8 (2%). Clade 8 was significantly associated with Shiga toxin bacteriophage insertion (SBI) type stx2 (locus of insertion, argW) in Argentinean isolates (P |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
unknown |
| ISSN: |
0099-2240 |
| Relation: |
Applied and Environmental Microbiology; Applied and Environmental Microbiology, 2012, 78 (13), pp. 4724 - 4731; http://hdl.handle.net/10453/113617 |
| Availability: |
http://hdl.handle.net/10453/113617 |
| Accession Number: |
edsbas.2CFE4DA4 |
| Database: |
BASE |