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Short-term forecasts to inform the response to the Covid-19 epidemic in the UK

Title: Short-term forecasts to inform the response to the Covid-19 epidemic in the UK
Authors: Funk, S; Abbott, S; Atkins, BD; Baguelin, M; Baillie, JK; Birrell, P; Blake, J; Bosse, NI; Burton, J; Carruthers, J; Davies, NG; De Angelis, D; Dyson, L; Edmunds, WJ; Eggo, RM; Ferguson, NM; Gaythorpe, K; Gorsich, E; Guyver-Fletcher, G; Hellewell, J; Hill, EM; Holmes, A; House, TA; Jewell, C; Jit, M; Jombart, T; Joshi, I; Keeling, MJ; Kendall, E; Knock, ES; Kucharski, AJ; Lythgoe, KA; Meakin, SR; Munday, JD; Openshaw, PJM; Overton, CE; Pagani, F; Pearson, J; Perez-Guzman, PN; Pellis, L; Scarabel, F; Semple, MG; Sherratt, K; Tang, M; Tildesley, MJ; Van Leeuwen, E; Whittles, LK
Publication Year: 2020
Collection: London School of Hygiene & Tropical Medicine: LSHTM Research Online
Description: Background Short-term forecasts of infectious disease can aid situational awareness and planning for outbreak response. Here, we report on multi-model forecasts of Covid-19 in the UK that were generated at regular intervals starting at the end of March 2020, in order to monitor expected healthcare utilisation and population impacts in real time. Methods We evaluated the performance of individual model forecasts generated between 24 March and 14 July 2020, using a variety of metrics including the weighted interval score as well as metrics that assess the calibration, sharpness, bias and absolute error of forecasts separately. We further combined the predictions from individual models into ensemble forecasts using a simple mean as well as a quantile regression average that aimed to maximise performance. We compared model performance to a null model of no change. Results In most cases, individual models performed better than the null model, and ensembles models were well calibrated and performed comparatively to the best individual models. The quantile regression average did not noticeably outperform the mean ensemble. Conclusions Ensembles of multi-model forecasts can inform the policy response to the Covid-19 pandemic by assessing future resource needs and expected population impact of morbidity and mortality.
Document Type: article in journal/newspaper
File Description: text
Language: English
ISSN: 1468-5833
Relation: https://researchonline.lshtm.ac.uk/id/eprint/4660335/1/Short-term%20forecasts%20to%20inform%20the%20response%20to%20the%20Covid-19%20epidemic%20in%20the%20UK.pdf; Funk, S ORCID logo; Abbott, S ORCID logo; Atkins, BD; Baguelin, M; Baillie, JKORCID logo; Birrell, P; Blake, J; Bosse, NI ORCID logo; Burton, JORCID logo; Carruthers, J; +37 more.Davies, NG ORCID logo; De Angelis, D; Dyson, L; Edmunds, WJ ORCID logo; Eggo, RM ORCID logo; Ferguson, NM; Gaythorpe, K; Gorsich, EORCID logo; Guyver-Fletcher, GORCID logo; Hellewell, J; Hill, EMORCID logo; Holmes, AORCID logo; House, TA; Jewell, C; Jit, M ORCID logo; Jombart, T; Joshi, I; Keeling, MJORCID logo; Kendall, E; Knock, ES; Kucharski, AJ; Lythgoe, KA; Meakin, SR ORCID logo; Munday, JDORCID logo; Openshaw, PJMORCID logo; Overton, CE; Pagani, FORCID logo; Pearson, J; Perez-Guzman, PN; Pellis, L; Scarabel, F; Semple, MGORCID logo; Sherratt, K ORCID logo; Tang, M; Tildesley, MJ; Van Leeuwen, E ORCID logo; and Whittles, LKORCID logo (2020) Short-term forecasts to inform the response to the Covid-19 epidemic in the UK. medRxiv preprint - BMJ Yale. ISSN 1468-5833 DOI:10.1101/2020.11.11.20220962
DOI: 10.1101/2020.11.11.20220962
Availability: https://researchonline.lshtm.ac.uk/id/eprint/4660335/; https://doi.org/10.1101/2020.11.11.20220962
Rights: cc_by
Accession Number: edsbas.2DAC8311
Database: BASE