| Title: |
Dyskinesia in multiple system atrophy and progressive supranuclear palsy |
| Authors: |
Jost, WH; Lingor, P; Tönges, L; Schwarz, J; Buhmann, C; Kassubek, J; Schrag, A |
| Source: |
Journal of Neural Transmission , 126 pp. 925-932. (2019) |
| Publication Year: |
2019 |
| Collection: |
University College London: UCL Discovery |
| Subject Terms: |
Dyskinesia; Multiple system atrophy; Parkinson’s disease; Progressive supranuclear palsy |
| Description: |
In the differential diagnosis of Parkinson syndromes, the response to L-Dopa is an essential criterion for the diagnosis of idiopathic Parkinson's syndrome (IPS), and the presence of L-Dopa-induced dyskinesia (LID) is considered a supportive criterion. This implies that in the presence of LID an atypical Parkinson-syndrome (APS) is unlikely. However, dyskinesia, and in particular LID, can also be present in APS such as MSA and PSP, although less frequently, and with varying clinical appearance. We conclude that whilst presence of dyskinesia provides support for a diagnosis of IPD, they do not allow reliable differentiation from APS. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10074429/1/Schrag_Dyskin_APS_vs2%20tracked.pdf; https://discovery.ucl.ac.uk/id/eprint/10074429/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10074429/1/Schrag_Dyskin_APS_vs2%20tracked.pdf; https://discovery.ucl.ac.uk/id/eprint/10074429/ |
| Rights: |
open |
| Accession Number: |
edsbas.2F7C8E16 |
| Database: |
BASE |