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Social pain and social gain in the adolescent brain: A common neural circuitry underlying both positive and negative social evaluation

Title: Social pain and social gain in the adolescent brain: A common neural circuitry underlying both positive and negative social evaluation
Authors: Dalgleish, T; Walsh, ND; Mobbs, D; Schweizer, S; Van Harmelen, AL; Dunn, B; Dunn, V; Goodyer, I; Stretton, J
Source: urn:ISSN:2045-2322 ; Scientific Reports, 7, 1, 42010
Publisher Information: Springer Nature
Publication Year: 2017
Collection: UNSW Sydney (The University of New South Wales): UNSWorks
Subject Terms: 5202 Biological Psychology; 52 Psychology; Behavioral and Social Science; Neurosciences; Chronic Pain; Basic Behavioral and Social Science; Mental Health; Pain Research; 1.1 Normal biological development and functioning; Adolescent; Adult; Brain; Brain Mapping; Female; Humans; Image Processing; Computer-Assisted; Magnetic Resonance Imaging; Male; Neural Pathways; Pain; Psychological Distance; Social Environment; Stress; Psychological; Task Performance and Analysis; Young Adult; anzsrc-for: 5202 Biological Psychology; anzsrc-for: 52 Psychology
Description: Social interaction inherently involves the subjective evaluation of cues salient to social inclusion and exclusion. Testifying to the importance of such social cues, parts of the neural system dedicated to the detection of physical pain, the dorsal anterior cingulate cortex (dACC) and anterior insula (AI), have been shown to be equally sensitive to the detection of social pain experienced after social exclusion. However, recent work suggests that this dACC-AI matrix may index any socially pertinent information. We directly tested the hypothesis that the dACC-AI would respond to cues of both inclusion and exclusion, using a novel social feedback fMRI paradigm in a population-derived sample of adolescents. We show that the dACC and left AI are commonly activated by feedback cues of inclusion and exclusion. Our findings suggest that theoretical accounts of the dACC-AI network as a neural alarm system restricted within the social domain to the processing of signals of exclusion require significant revision.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: unknown
Relation: https://hdl.handle.net/1959.4/unsworks_57927; https://doi.org/10.1038/srep42010
DOI: 10.1038/srep42010
Availability: https://hdl.handle.net/1959.4/unsworks_57927; https://unsworks.unsw.edu.au/bitstreams/a685fb2a-2eee-4d21-b642-b742d0200908/download; https://doi.org/10.1038/srep42010
Rights: open access ; https://purl.org/coar/access_right/c_abf2 ; CC BY ; https://creativecommons.org/licenses/by/4.0/ ; free_to_read
Accession Number: edsbas.303C147B
Database: BASE