| Title: |
Cerebral and peripheral vascular differences between pre- and post-menopausal women |
| Authors: |
Brislane, Á; Low, DA; Carter, SE; Holder, SM; Jones, H; Hopkins, ND |
| Publisher Information: |
Lippincott, Williams & Wilkins |
| Publication Year: |
2019 |
| Collection: |
Liverpool John Moores University: LJMU Research Online |
| Subject Terms: |
R Medicine (General); RC1200 Sports Medicine |
| Description: |
Objective: Menopause is associated with lower peripheral vascular function however cerebrovascular responses to this time-period are unclear. We aimed to describe peripheral vascular and cerebrovascular differences between pre- and post-menopausal women. Methods: Fifty pre- and post-menopausal women (N=100) underwent assessments of cerebral blood flow, cerebrovascular reactivity and autoregulation, carotid artery reactivity, brachial and femoral artery flow-mediated dilation and carotid, brachial and femoral artery intima-media thickness. Comparisons were made between pre- and post-menopausal women followed by a secondary-analysis (N=20) between late-pre-menopausal women and those within five years of menopause using a general linear model. Results: Cerebral blood flow (-11 [-17, -4 cm/s]; p=0.03) and carotid reactivity (-2.3 [-4.3, - 0.3%] p=0.03) were lower post-menopause compared to pre-menopause while cerebrovascular reactivity and autoregulation did not differ (p>0.05). Post-menopausal women had a larger carotid (0.16 [0.13, 0.20 mm] p |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| ISSN: |
1072-3714 |
| Relation: |
https://researchonline.ljmu.ac.uk/id/eprint/11267/1/Brislane_Menopause.pdf; Brislane, Á, Low, DA, Carter, SE, Holder, SM, Jones, H and Hopkins, ND (2019) Cerebral and peripheral vascular differences between pre- and post-menopausal women. Menopause: The Journal of the North American Menopause Society. ISSN 1072-3714 |
| DOI: |
10.1097/GME.0000000000001442 |
| Availability: |
https://researchonline.ljmu.ac.uk/id/eprint/11267/; https://researchonline.ljmu.ac.uk/id/eprint/11267/1/Brislane_Menopause.pdf; https://doi.org/10.1097/GME.0000000000001442 |
| Accession Number: |
edsbas.30E92881 |
| Database: |
BASE |