| Title: |
The epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century |
| Authors: |
Caini, Saverio; Kusznierz, Gabriela; Garate, Verònica Vera; Wangchuk, Sonam; Thapa, Binay; de Paula Júnior, Francisco José; Ferreira de Almeida, Walquiria Aparecida; Njouom, Richard; Fasce, Rodrigo, A.; Bustos, Patricia; Feng, Luzhao; Peng, Zhibin; Araya, Jenny Lara; Bruno, Alfredo; de Mora, Doménica; Barahona de Gámez, Mónica Jeannette; Pebody, Richard; Zambon, Maria; Higueros, Rocio; Rivera, Rudevelinda; Kosasih, Herman; Castrucci, Maria Rita; Bella, Antonino; Kadjo, Hervé, A.; Daouda, Coulibaly; Makusheva, Ainash; Bessonova, Olga; Chaves, Sandra, S.; Emukule, Gideon, O.; Heraud, Jean-Michel; Razanajatovo, Norosoa, H.; Barakat, Amal; El Falaki, Fatima; Meijer, Adam; Donker, Gé, A.; Huang, Q. Sue; Wood, Tim; Balmaseda, Angel; Palekar, Rakhee; Arévalo, Brechla Moreno; Rodrigues, Ana Paula; Guiomar, Raquel; Lee, Vernon Jian Ming; Ang, Li Wei; Cohen, Cheryl; Treurnicht, Florette; Mironenko, Alla; Holubka, Olha; Bresee, Joseph; Brammer, Lynnette; Le, Mai, T. Q.; Hoang, Phuong, V. M.; El Guerche-Séblain, Clotilde; Paget, John; Study Team, The Global Influenza B |
| Contributors: |
Netherlands Institute for Health Services Research Utrecht (NIVEL); Instituto Nacional de Enfermedades Respiratorias Dr. Emilio Coni Santa Fe, Argentina (INER); Ministry of Health Bhoutan; Ministry of Health Brasília, Brazil; Centre Pasteur du Cameroun; Pasteur Network (Réseau International des Instituts Pasteur); Instituto de Salud Pública de Chile (ISP); Chinese Center for Disease Control and Prevention; Ministry of Health Costa Rica; Instituto Nacional de Investigación en Salud Pública Guayaquil, Ecuador (INSPI); Ministerio de Salud de El Salvador (MINSAL); Public Health England London; Ministerio de Salud Publica y Asistencia Social Guatemala (MSPAS); Ministry of Health Honduras (SESAL); US Naval Medical Research Unit No.2 Jakarta, Indonesia (NAMRU-2); Naval Medical Research Center Silver Spring, USA (NMRC); Istituto Superiore di Sanità = National Institute of Health (ISS); Institut Pasteur de Côte d'Ivoire; Institut National de Santé Publique d'Abidjan-INSP; Ministry of Healthcare Kazakhstan; Centers for Disease Control and Prevention Atlanta (CDC); Centers for Disease Control and Prevention; Centers for Disease Control and Prevention Kenya; Unité de Virologie Antananarivo, Madagascar; Institut Pasteur de Madagascar; Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur); Institut National d'Hygiène Maroc; National Institute for Public Health and the Environment Bilthoven (RIVM); Institute of Environmental Science and Research Wellington, New Zealand (ESR); Ministry of Health Nicaragua (MINSA); Organisation Panaméricaine de la Santé (Organisation Mondiale de la Santé, Bureau régional des Amériques) - Pan American Health Organization (Regional Office for the Americas of the World Health Organization) Washington (PAHO / WHO - OPS / OMS); Organisation Mondiale de la Santé / World Health Organization Office Genève, Suisse (OMS / WHO); Instituto Conmemorativo Gorgas de Estudios de la Salud Panamá; Instituto Nacional de Saùde Dr Ricardo Jorge Portugal (INSA); Ministry of Health Singapore; National Institute for Communicable Diseases Johannesburg (NICD); University of the Witwatersrand Johannesburg (WITS); National Academy of Sciences of Ukraine = Національна академія наук України = Académie nationale des sciences d'Ukraine (NASU / НАН України); National Institute of Hygiene and Epidemiology / Institut National d'Hygiène et d'Épidémiologie Hanoi, Vietnam (NIHE); Sanofi Pasteur Lyon, France; The study is supported by a research grant from Sanofi Pasteur: the ‘Global Epidemiology of Influenza B’ research project. The funder provided support in the form of salaries for two authors (CEGS and JP) but did not have any additional role in the data collection, analysis, decision to publish, or preparation of the manuscript.; The “Global Influenza B Study team” (group authorship) includes the following scientists: Juan Manuel Rudi (jmrudi@anlis.gov.ar), National Institute of Respiratory Diseases "Emilio Coni", Santa Fe, Argentina; Dorji Wangchuk (dorjiwangchuk@health.gov.bt) and Sangay Zangmo (szangmo@health.gov.bt), Royal Centre for Disease Control, Department of Public Health, Ministry of Health, Thimphu, Bhutan; Daiana Araujo da Silva (daiana.silva@saude.gov.br), Ministry of Health, Department of Surveillance of Transmissible Diseases, Brasília/DF, Brazil; Winston Andrade (wandrade@ispch.cl), Sub-Department of Viral Diseases, Instituto de Salud Pública de Chile, Santiago, Chile; Jiandong Zheng (zhengjd@chinacdc.cn) and Ying Qin (qinying@chinacdc.cn), Division of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, P.R. China; Joanna Ellis (joanna.ellis@phe.gov.uk), Public Health England, London, United Kingdom; Simona Puzelli (simona.puzelli@iss.it), National Influenza Center, Department of Infectious Diseases, National Institute of Health, Rome, Italy; Caterina Rizzo (rizzocaterina@gmail.com), Bambino Gesù Children's Hospital, Rome, Italy; Linus Ndegwa (ikf7@cdc.gov), Influenza Program, Centers for Disease Control and Prevention, Nairobi, Kenya; Marit MA de Lange (marit.de.lange@rivm.nl) and Anne C. Teirlinck (anne.teirlinck@rivm.nl), National Institute for Public Health and the Environment, Centre for Infectious Diseases, Epidemiology and Surveillance, Bilthoven, The Netherlands; Jeffery Cutter (jeffery_cutter@moh.gov.sg) and Raymond Tzer Pin Lin (raymond_lin@moh.gov.sg), Public Health Group, Ministry of Health, Singapore, Singapore; Than T. Le (lmot82@yahoo.com), National Institute of Hygiene and Epidemiology, Hanoi, Vietnam; Peter Kinuthia 42 (polorien@gmail.com), IHRC Inc., Atlanta, USA. |
| Source: |
ISSN: 1932-6203. |
| Publisher Information: |
CCSD; Public Library of Science |
| Publication Year: |
2019 |
| Collection: |
Réseau International des Instituts Pasteur, Paris: HAL-RIIP |
| Subject Terms: |
MESH: Epidemics; MESH: Epidemiological Monitoring; MESH: Male; MESH: Population Surveillance; MESH: Seasons; MESH: Female; MESH: History; MESH: Humans; MESH: Influenza A Virus; H1N1 Subtype; MESH: Influenza B virus; MESH: Influenza Vaccines; MESH: Influenza; Human; [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology; [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry; Molecular Biology/Molecular biology; [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases; [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| Time: |
21st Century |
| Description: |
International audience ; We describe the epidemiological characteristics, pattern of circulation, and geographical distribution of influenza B viruses and its lineages using data from the Global Influenza B Study. We included over 1.8 million influenza cases occurred in thirty-one countries during 2000-2018. We calculated the proportion of cases caused by influenza B and its lineages; determined the timing of influenza A and B epidemics; compared the age distribution of B/ Victoria and B/Yamagata cases; and evaluated the frequency of lineage-level mismatch for the trivalent vaccine. The median proportion of influenza cases caused by influenza B virus was 23.4%, with a tendency (borderline statistical significance, p = 0.060) to be higher in tropical vs. temperate countries. Influenza B was the dominant virus type in about one every seven seasons. In temperate countries, influenza B epidemics occurred on average three weeks later than influenza A epidemics; no consistent pattern emerged in the tropics. The two B lineages caused a comparable proportion of influenza B cases globally, however the B/Yamagata was more frequent in temperate countries, and the B/Victoria in the tropics (p = 0.048). B/Yamagata patients were significantly older than B/Victoria patients in almost all countries. A lineage-level vaccine mismatch was observed in over 40% of seasons in temperate countries and in 30% of seasons in the tropics. The type B virus caused a substantial proportion of influenza infections globally in the 21 st century, and its two virus lineages differed in terms of age and geographical distribution of patients. These findings will help inform health policy decisions aiming to reduce disease burden associated with seasonal influenza. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/31513690; PUBMED: 31513690; PUBMEDCENTRAL: PMC6742362 |
| DOI: |
10.1371/journal.pone.0222381 |
| Availability: |
https://pasteur.hal.science/pasteur-03254270; https://pasteur.hal.science/pasteur-03254270v1/document; https://pasteur.hal.science/pasteur-03254270v1/file/Caini_S_Plosone2019.pdf; https://doi.org/10.1371/journal.pone.0222381 |
| Rights: |
https://creativecommons.org/publicdomain/zero/1.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.313961A8 |
| Database: |
BASE |