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Prognostic value of residual disease (RD) biology and gene expression changes during the neoadjuvant treatment in patients with HER2-positive early breast cancer (EBC).

Title: Prognostic value of residual disease (RD) biology and gene expression changes during the neoadjuvant treatment in patients with HER2-positive early breast cancer (EBC).
Authors: Fernandez-Martinez, Aranzazu; Tanioka, M; Ahn, Sung-gwe; Zagami, Paola; Pascual, T; Rediti, Mattia; Tang, G; Hoadley, Katherine A; Venet, D; Rashid, N U; Spears, P A; Di Cosimo, S; de Azambuja, Evandro; Choudhury, A; Rastogi, P; Islam, Md Naimul; Cortes, J; Llombart-Cussac, A; Swain, S M; Sotiriou, Christos; Prat, A; Perou, Charles M; Carey, Lisa A
Source: Annals of oncology
Publication Year: 2024
Collection: DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB)
Subject Terms: Sciences bio-médicales et agricoles; HER2-positive early breast cancer; gene expression; genomic biomarkers; post-treatment; prognostic; residual disease
Description: In human epidermal growth factor receptor 2 (HER2)-positive early breast cancer (EBC), we investigated tumor and immune changes during neoadjuvant treatment and their impact on residual disease (RD) biology and prognostic implications across four neoadjuvant studies of trastuzumab with or without lapatinib, and with or without chemotherapy: CALGB 40601, PAMELA, NeoALTTO, and NSABP B-41. ; SCOPUS: ar.j ; info:eu-repo/semantics/published
Document Type: article in journal/newspaper
File Description: 1 full-text file(s): application/pdf
Language: English
Relation: uri/info:doi/10.1016/j.annonc.2024.12.010; uri/info:pmid/39706338; uri/info:scp/85216294300; https://dipot.ulb.ac.be/dspace/bitstream/2013/387946/1/doi_371590.pdf
Availability: https://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/387946; https://dipot.ulb.ac.be/dspace/bitstream/2013/387946/1/doi_371590.pdf
Accession Number: edsbas.32445052
Database: BASE