| Title: |
Effect of Bariatric Surgery on Survival and Hospitalizations in Patients with Severe Obesity. A Retrospective Cohort Study |
| Authors: |
Migliore, Enrica; Brunani, Amelia; Ciccone, Giovannino; Pagano, Eva; Arolfo, Simone; Rosso, Tiziana; Pellegrini, Marianna; Capodaglio, Paolo; Morino, Mario; Ghigo, Ezio; Bo, Simona |
| Contributors: |
E. Migliore; A. Brunani; G. Ciccone; E. Pagano; S. Arolfo; T. Rosso; M. Pellegrini; P. Capodaglio; M. Morino; E. Ghigo; S. Bo |
| Publisher Information: |
MDPI |
| Publication Year: |
2021 |
| Collection: |
The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| Subject Terms: |
Bariatric surgery; Hospitalization; Overall survival; Roux-en-Y gastric bypa; Sleeve gastrectomy; Settore MEDS-19/B - Medicina fisica e riabilitativa |
| Description: |
Bariatric surgery (BS) confers a survival benefit in specific subsets of patients with severe obesity; otherwise, effects on hospital admissions are still uncertain. We assessed the long-term effect on mortality and on hospitalization of BS in patients with severe obesity. This was a retrospective cohort study, including all patients residing in Piedmont (age 18–60 years, BMI ≥ 40 kg/m2) admitted during 2002–2018 to the Istituto Auxologico Italiano. Adjusted hazard ratios (HR) for BS were estimated for mortality and hospitalization, considering surgery as a time-varying variable. Out of 2285 patients, 331 (14.5%) underwent BS; 64.4% received sleeve gastrectomy (SG), 18.7% Roux-en-Y gastric bypass (RYGB), and 16.9% adjustable gastric banding (AGB). After 10-year fol-low-up, 10 (3%) and 233 (12%) patients from BS and non-BS groups died, respectively (HR = 0.52; 95%CI 0.27–0.98, by a multivariable Cox proportional-hazards regression model). In patients undergoing SG or RYGB, the hospitalization probability decreased significantly in the after-BS group (HR = 0.77; 0.68–0.88 and HR = 0.78; 0.63–0.98, respectively) compared to non-BS group. When comparing hospitalization risk in the BS group only, a marked reduction after surgery was found for all BS types. In conclusion, BS significantly reduced the risk of all-cause mortality and hospitalization after 10-year fol-low-up. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/34579025; info:eu-repo/semantics/altIdentifier/wos/WOS:000701109200001; volume:13; issue:9; firstpage:1; lastpage:14; numberofpages:14; journal:NUTRIENTS; https://hdl.handle.net/2434/1118455 |
| DOI: |
10.3390/nu13093150 |
| Availability: |
https://hdl.handle.net/2434/1118455; https://doi.org/10.3390/nu13093150 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.329621CB |
| Database: |
BASE |