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A core outcome set for airway management research

Title: A core outcome set for airway management research
Authors: Hansel, Jan; Fuchs, Alexander; Cornwell, Benjamin; Haynes, Katherine; Tanna, Vinay; Mohamed, Ahmed; Rivett, Kate; Radcliffe, Gillian; Greif, Robert; Cook, Tim M; El-Boghdadly, Kariem
Source: Hansel, J, Fuchs, A, Cornwell, B, Haynes, K, Tanna, V, Mohamed, A, Rivett, K, Radcliffe, G, Greif, R, Cook, T M, El-Boghdadly, K 2026, 'A core outcome set for airway management research', Anaesthesia, vol. 81, no. 3, pp. 373-382. https://doi.org/10.1111/anae.70026
Publication Year: 2026
Collection: University of Bristol: Bristol Reserach
Description: Introduction: Airway management research has historically incorporated heterogeneous outcome selection and definitions. This impedes evidence synthesis and hinders advances in patient care. We aimed to develop a core outcome set to standardise airway management research and improve outcome reporting. Methods: We performed a systematic review of outcomes reported in airway management studies to identify candidate outcomes from a random sample of eligible studies. We used a modified Delphi survey of three key stakeholder groups: patients with experience of airway management; clinicians engaged in airway management; and others (including researchers, device manufacturers and policymakers). Outcomes were classified into five domains: procedural effectiveness; physiological parameters; adverse events; patient-reported outcomes; and other. Outcomes were presented in random order in two sequential virtual Delphi surveys and rated by each respondent. Candidate outcome measurement instruments were identified through included studies and targeted literature searches. Subsequently, a core outcome set with suggested outcome measurement instruments was discussed and agreed. Results: The systematic review identified 4368 studies, with 68 candidate outcomes longlisted from a random sample of 100 studies. Rounds one and two Delphi surveys were completed by 453 and 155 participants, respectively, from six continents. First and second virtual panels were attended by 62 and 44 participants, respectively. The final agreed core outcome set included 11 outcomes: death; cardiac arrest; serious complications; pulmonary complications; neurological complications; airway trauma; unrecognised oesophageal intubation; hypoxaemia; first attempt success without complications; overall success without complications; and difficult airway. Proposed outcome measurement instruments were agreed for all included outcomes. Discussion: We present the first consensus-based core outcome set for airway management research, with agreed definitions and ...
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/41199615; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1983/608a569c-5272-4e37-b1a7-4d1d8f8a398d
DOI: 10.1111/anae.70026
Availability: https://hdl.handle.net/1983/608a569c-5272-4e37-b1a7-4d1d8f8a398d; https://research-information.bris.ac.uk/en/publications/608a569c-5272-4e37-b1a7-4d1d8f8a398d; https://doi.org/10.1111/anae.70026
Rights: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.329CF6D9
Database: BASE