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Geo-temporal study of clinical malaria in an endemic zone in southern Mali: The case of the Kolondieba health district from 2019 to 2021

Title: Geo-temporal study of clinical malaria in an endemic zone in southern Mali: The case of the Kolondieba health district from 2019 to 2021
Authors: Berthé, Ibrahima; Cissoko, Mady; Koné, Mamady; Mbaga, Donatien Serge; Diaby, Alou; Konaté, Abdramane; Théra, Ismaila; Haidara, Bayaya; Ongoiba, Abdoulaye; Togola, Tahirou; Diarra, Modibo; Togola, Ousmane Boua; Dolo, Amagoron dit Mathias; Diarra, Souleymane; Koné, Bourahima; Koné, Yacouba; Sissoko, Lassana; Rabarijaona, Leon Paul; Coulibaly, Cheick Abou; Traore, Cheick Amadou Tidiane; Sagara, Issaka
Publisher Information: Dutch Malaria Foundation
Publication Year: 2025
Collection: Zenodo
Subject Terms: malaria; mali; geo-temporal
Description: Background. Malaria remains a significant public health challenge in Mali, particularly in endemic areas such as the Kolondieba health district. This study aimed to analyse the geo-temporal dynamics of clinical malaria transmission, identifying high-risk periods, vulnerable age groups and associated environmental and health determinants. Materials and Methods. A historical cohort study was conducted from 2019 to 2021 across 21 health facilities in the Kolondieba district. Epidemiological, climatic, and demographic data were analysed using geospatial tools (QGIS) and statistical software (R). The non-parametric Wilcoxon and Kruskall-Wallis tests were used to compare two means and population malaria incidence distribution, respectively. Results. The incidence of malaria exhibited seasonality influenced by precipitation and humidity, while elevated temperatures were associated with a decrease in malaria incidence. Periods of high transmission potential (HTP) last for 20-25 weeks annually (weeks 23-48) and peak around weeks 30-31. Malaria accounted for 53.71% of consultation reasons, with pronounced vulnerability observed in children aged 0-4 yrs, especially during high transmission periods. Spatial stratification revealed two risk levels: 5 health areas at moderate risk (incidence 251-450 cases/1000 inhabitants) and 16 at high risk (>450 cases/1000 inhabitants). Health center attendance was a more determining risk factor. Conclusion. This study highlights the spatial and temporal heterogeneity of malaria transmission in southern Mali, emphasising the necessity to target interventions during weeks 23-48 (June through November), among children
Document Type: article in journal/newspaper
Language: unknown
ISSN: 2214-4374
Relation: https://zenodo.org/records/15676301; oai:zenodo.org:15676301; PMC12107291; https://doi.org/10.5281/zenodo.15676301
DOI: 10.5281/zenodo.15676301
Availability: https://doi.org/10.5281/zenodo.15676301; https://zenodo.org/records/15676301
Rights: Creative Commons Attribution 4.0 International ; cc-by-4.0 ; https://creativecommons.org/licenses/by/4.0/legalcode
Accession Number: edsbas.33B74EED
Database: BASE