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How efficacious is the combination of substitute bone graft with autogenous bone graft in comparison with substitute bone graft alone in the horizontal bone gain? A systematic review and meta-analysis

Title: How efficacious is the combination of substitute bone graft with autogenous bone graft in comparison with substitute bone graft alone in the horizontal bone gain? A systematic review and meta-analysis
Authors: Meza-Mauricio, J.; Furquim, C.-P.; dos Reis, L.-D.; Maximiano, M.-M.-H.; Mendoza-Azpur, G.; Muniz, F.-W.-M.-G.; Rasperini, G.; Faveri, M.
Publisher Information: Medicina Oral
Publication Year: 2022
Collection: Universidad Científica del Sur, Peru: Repositorio Académico
Subject Terms: Implant Innovations in Orthodontics and Bone Health; Guided Bone Regeneration Techniques for Implant Success; https://purl.org/pe-repo/ocde/ford#3.02.14
Description: Background: A systematic review (SR) was conducted to answer the following focused question based on PICO strategy: In patients who were submitted to horizontal guided bone regeneration, “how efficacious is the combination of substitute bone graft with autogenous bone graft in comparison with substitute bone graft alone, in terms of bone gain?” Material and Methods: MEDLINE (PubMed), Scopus, Embase, Web of Science databases were searched, and hand searches were made up to June 2021, to find randomized clinical trials comparing the clinical effects of autogenous bone graft + substitute bone graft versus substitute bone graft alone in the treatment of horizontal guided bone regeneration. Results: Four trials representing 109 individuals were included. All studies included in this SR used allogeneic bone graft. The meta-analysis did not show any statistically significant difference between the groups, for horizontal bone gain at a distance of 0 mm (MD: -0.46; 95%CI: -1.03 – 0.11) or at a distance of 4 to 5 mm from the top of the crestal alveolar ridge (MD: 0.17; 95%CI: -1.08 – 1.42). Conclusions: Within limitations of this systematic review, it was concluded that the addition of autogenous bone graft to the allogeneic bone graft did not significantly increase the quantity of regenerated bone.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
ISSN: 1989-5488
Relation: urn:issn:1989-5488; https://hdl.handle.net/20.500.12805/5296; https://doi.org/10.4317/jced.59087; Journal of Clinical and Experimental Dentistry
DOI: 10.4317/jced.59087
Availability: https://hdl.handle.net/20.500.12805/5296; https://doi.org/10.4317/jced.59087
Rights: https://purl.org/coar/access_right/c_abf2 ; https://creativecommons.org/licenses/by-nc-sa/4.0/
Accession Number: edsbas.33C985A8
Database: BASE