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P18 Antibiotic duration exceeds time to clinical stability in hospital acquired pneumonia

Title: P18 Antibiotic duration exceeds time to clinical stability in hospital acquired pneumonia
Authors: Lewis-Douglas, Elliott; Spedding, Jon; Prem, Sandhya; Lupton, Jamie; Weiand, Daniel; McCullagh, Iain; Hellyer, Tom
Source: JAC-Antimicrobial Resistance ; volume 7, issue Supplement_4 ; ISSN 2632-1823
Publisher Information: Oxford University Press (OUP)
Publication Year: 2025
Description: Background Hospital-acquired pneumonia (HAP) is a common indication for broad-spectrum antibiotics.1 Shorter course durations are becoming more widely accepted due to increasing evidence of non-inferior clinical effectiveness and safety compared to longer course lengths.2,3 Guidance for duration in HAP is often extrapolated from CAP and VAP evidence, and HAP lacks validated scoring systems to guide decision making.4,5 Time to clinical stability (TCS) criteria (heart rate 90 mmHg, temperature 24 h. Twenty-five percent of patients had a change from initial antibiotic, ...
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/jacamr/dlaf230.025
Availability: https://doi.org/10.1093/jacamr/dlaf230.025; https://academic.oup.com/jacamr/article-pdf/7/Supplement_4/dlaf230.025/65727805/dlaf230.025.pdf
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.33FD7B59
Database: BASE