| Title: |
Nutritional status and quality of life of patients with advanced gastroenteropancreatic neuroendocrine neoplasms in Spain: the NUTRIGETNE (GETNE-S2109) study |
| Authors: |
Olmo García, María Isabel del; Hernández Rienda, Lorena; Garcia Carbonero, Rocio; Hernando, Jorge; Custodio, Ana; Anton Pascual, Beatriz; Gómez, Marta; Palma Milla, Samara; Suarez, Lorena; Bellver, Marta; Alonso, Vicente; Serrano, Raquel; Valdés, Nuria; Melián, Marcos; Febrero, Beatriz; Sampedro Nuñez, Miguel Antonio; Biarnes, Josefina; Díaz Pérez, José Ángel; Molina Cerrillo, Javier; López López, Carlos; Martínez Olmos, Miguel Ángel; Merino Torres, Juan Francisco; Capdevila, Jaume; Argente Pla, María; Nutrigetne Group |
| Source: |
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Collection: |
Dipòsit Digital de la Universitat de Barcelona |
| Subject Terms: |
Avaluació de l'estat nutricional; Neuroendocrinologia; Tumors; Nutritional status measurement; Neuroendocrinology |
| Description: |
Patients with advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have impaired nutritional and physical performance due to the cancer pathophysiology and its treatment. The NUTRIGETNE study sought to characterize the nutritional status of patients with advanced GEP-NENs in Spain. This is a cross-sectional study that included patients with advanced GEP-NENs receiving active oncological treatment. Patients had a complete physical examination, anthropometry, bioelectrical impedance, dynamometry, laboratory analysis, and a comprehensive nutritional risk assessment. Malnutrition was defined according to Global Leadership Initiative on Malnutrition (GLIM) criteria. The study included 399 patients out of the 400 planned (Pearson's chi 2; alpha 0.05). Median age was 62 years (22-83). Tumors most commonly originated in the small intestine (43.9%) and the pancreas (41.6%), 94.7% were metastatic, and 36.7%, 49.4%, and 12.5% were G1, G2, and G3, respectively. Malnutrition prevalence was 61.9% (25.8% moderate; 36.1% severe), mainly due to low muscle mass (50.9%), which was the most prevalent GLIM phenotypic criteria. Moreover, malnutrition showed a correlation with decreased hand grip strength (mean 23 vs 31.9 kg; P |
| Document Type: |
article in journal/newspaper |
| File Description: |
12 p.; application/pdf |
| Language: |
English |
| Relation: |
Reproducció del document publicat a: https://doi.org/10.1093/oncolo/oyae343; The Oncologist, 2025, vol. 30, num. 2; https://doi.org/10.1093/oncolo/oyae343; https://hdl.handle.net/2445/221346 |
| Availability: |
https://hdl.handle.net/2445/221346 |
| Rights: |
cc-by-nc (c) Olmo García et al., 2025 ; http://creativecommons.org/licenses/by-nc-nd/4.0/ ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.35F24C04 |
| Database: |
BASE |