| Title: |
Developmental transcriptional atlas of the Drosophila melanogaster VNC (neurons - loom version) |
| Authors: |
Cachero, Sebastian; Donà, Erika |
| Contributors: |
Mitletton, Myrto; Jefferis, Gregory |
| Publisher Information: |
Zenodo |
| Publication Year: |
2025 |
| Collection: |
Zenodo |
| Description: |
This object contains scRNA-seq counts data of the Drosophil malanogaster VNC atlas presented in "A Developmental Atlas of the Drosophila Nerve Cord Uncovers a Global Temporal Code for Neuronal Identity" (Cachero et al. 2025, doi.org/10.1101/2025.07.16.664682). This dataset comprises neurons and neuronal precursors. Data were collected from 92 individual animals, covering four developmental stages (6, 24, 36 and 48 hours after puparium formation) and both sexes. Each stage–sex condition is represented by 5 to 18 biological replicates, covering between 5 to 11 different genotypes. Two umap embeddings are stored in the object: UMAPallages: calculated before stage integrationumap: calculated after integration Cellular metadata: Sex: sex of the animal the cell originated fromStage: developmental stage of the animal the cell originated frombirthtime: predicted neurogenesys period (primary, early secondary, secondary)maturation: maturation state of the neuronhemilineage: predicted hemilineagehemilineage_stem: predicted hemilineage for less mature neurons subsetsoma_neuromere: predicted soma neuromereprecursorsType: whether neuroblast (NB), ganglion mother cell (GMC), immature post mitotic neuron (earlyNeuron) or more mature neuron (neuron). Applies only to precursors subsetfru_clone: fruitless clone predicted identityfru_dsx: whether neuron expresses fru, dsx or both. Applies only to secondary neuronsamines: predicted aminergic identityneurotransmitter: predicted neurotransmitter identity |
| Document Type: |
dataset |
| Language: |
unknown |
| Relation: |
https://zenodo.org/communities/devdrosneuro-scrnaseq/; https://zenodo.org/records/17184090; oai:zenodo.org:17184090; https://doi.org/10.5281/zenodo.17184090 |
| DOI: |
10.5281/zenodo.17184090 |
| Availability: |
https://doi.org/10.5281/zenodo.17184090; https://zenodo.org/records/17184090 |
| Rights: |
Creative Commons Zero v1.0 Universal ; cc0-1.0 ; https://creativecommons.org/publicdomain/zero/1.0/legalcode |
| Accession Number: |
edsbas.35F705A0 |
| Database: |
BASE |