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Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis

Title: Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis
Authors: Garin, Noe; Zarate-Tamames, Borja; Gras-Martin, Laura; Milà, Raimon; Crespo Lessmann, Astrid; Curto Sánchez, Elena; Hernández Hernández, Marta; Mestres, Concepció; Plaza, Vicente; Universitat Autònoma de Barcelona
Publication Year: 2023
Collection: Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB
Subject Terms: Asthma; Clinical outcomes; COPD; Electronic monitoring device; Meta-analysis; Medication adherence
Description: We conducted a systematic review and meta-analysis to gain insight into the characteristics and clinical impact of electronic monitoring devices of inhalers (EMDs) and their clinical interventions in adult patients with asthma or COPD. The search included PubMed, Web of Science, Cochrane, Scopus and Embase databases, as well as official EMDs websites. We found eight observational studies and ten clinical trials, assessing a wide range of clinical outcomes. Results from the meta-analysis on adherence to inhalers in a period over three months were favourable in the EMD group (fixed effects model: SMD: 0.36 [0.25-0.48]; random effects model SMD: 0.41 [0.22-0.60]). An exploratory meta-analysis found an improvement in ACT score (fixed effect model SMD: 0.25 [0.11-0.39]; random effects model: SMD: 0.47 [-0.14-1.08]). Other clinical outcomes showed mixed results in the descriptive analyses. The findings of this review highlight the benefits of EMDs in the optimization of adherence to inhaled therapy as well as the potential interest in other clinical outcomes.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
Relation: Pharmaceuticals; Vol. 16 (march 2023); https://ddd.uab.cat/record/281409; urn:10.3390/ph16030414; urn:oai:ddd.uab.cat:281409; urn:pmcid:PMC10055893; urn:pmid:36986513; urn:oai:pubmedcentral.nih.gov:10055893; urn:scopus_id:85151660803
Availability: https://ddd.uab.cat/record/281409
Rights: open access ; Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. ; https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.36ADE525
Database: BASE