Heatmaps of the top 30 methylation markers with the highest C-index in tissue and plasma cohorts.
| Title: | Heatmaps of the top 30 methylation markers with the highest C-index in tissue and plasma cohorts. |
|---|---|
| Authors: | Ran Hu; Benjamin Tran; Shuo Li; Mary L. Stackpole; Weihua Zeng; Yonggang Zhou; Andrew Melehy; Saeed Sadeghi; Richard S. Finn; Xianghong Jasmine Zhou; Wenyuan Li; Vatche G. Agopian |
| Publication Year: | 2025 |
| Subject Terms: | Biophysics; Cell Biology; Genetics; Biotechnology; Developmental Biology; Cancer; Infectious Diseases; Virology; Mathematical Sciences not elsewhere classified; staging significantly improved; radiographic imaging features; peripheral blood draw; multivariate cox model; improve treatment decision; early cancer diagnosis; discriminating patient outcomes; critical unmet need; cancer genome atlas; based risk score; 80 &# 8211; 68 &# 8211; pilot study demonstrating; new prognostic biomarkers; identified 158 hcc; 377 hcc tumors; noninvasive prognostic assessments; potential clinical utility; plasma cfdna samples; hepatocellular carcinoma based; stratify hcc patients |
| Description: | (A) Methylation status in the patient cohort with tissue samples. (B) Methylation status in the patient cohort with plasma samples. Samples (columns) are sorted by risk score. The marker index name and the concordance index (C-index) for each marker are annotated in the heatmap rows. Higher C-index values indicating stronger predictive power for survival. (TIF) |
| Document Type: | still image |
| Language: | unknown |
| DOI: | 10.1371/journal.pone.0321736.s002 |
| Availability: | https://doi.org/10.1371/journal.pone.0321736.s002; https://figshare.com/articles/figure/Heatmaps_of_the_top_30_methylation_markers_with_the_highest_C-index_in_tissue_and_plasma_cohorts_/28872224 |
| Rights: | CC BY 4.0 |
| Accession Number: | edsbas.36C6AD73 |
| Database: | BASE |