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Lower-Limb Amputees Adjust Quiet Stance in Response to Manipulations of Plantar Sensation

Title: Lower-Limb Amputees Adjust Quiet Stance in Response to Manipulations of Plantar Sensation
Authors: Shell, Courtney E.; Christie, Breanne P.; Marasco, Paul D.; Charkhkar, Hamid; Triolo, Ronald J.
Contributors: Defense Advanced Research Projects Agency; Space and Naval Warfare Systems Command; U.S. Department of Defense
Source: Frontiers in Neuroscience ; volume 15 ; ISSN 1662-453X
Publisher Information: Frontiers Media SA
Publication Year: 2021
Collection: Frontiers (Publisher - via CrossRef)
Description: Interfering with or temporarily eliminating foot-sole tactile sensations causes postural adjustments. Furthermore, individuals with impaired or missing foot-sole sensation, such as lower-limb amputees, exhibit greater postural instability than those with intact sensation. Our group has developed a method of providing tactile feedback sensations projected to the missing foot of lower-limb amputees via electrical peripheral nerve stimulation (PNS) using implanted nerve cuff electrodes. As a step toward effective implementation of the system in rehabilitation and everyday use, we compared postural adjustments made in response to tactile sensations on the missing foot elicited by our system, vibration on the intact foot-sole, and a control condition in which no additional sensory input was applied. Three transtibial amputees with at least a year of experience with tactile sensations provided by our PNS system participated in the study. Participants stood quietly with their eyes closed on their everyday prosthesis while electrically elicited, vibratory, or no additional sensory input was administered for 20 s. Early and steady-state postural adjustments were quantified by center of pressure location, path length, and average angle over the course of each trial. Electrically elicited tactile sensations and vibration both caused shifts in center of pressure location compared to the control condition. Initial (first 3 s) shifts in center of pressure location with electrically elicited or vibratory sensory inputs often differed from shifts measured over the full 20 s trial. Over the full trial, participants generally shifted toward the foot receiving additional sensory input, regardless of stimulation type. Similarities between responses to electrically elicited tactile sensations projected to the missing foot and responses to vibration in analogous regions on the intact foot suggest that the motor control system treats electrically elicited tactile inputs similarly to native tactile inputs. The ability of electrically ...
Document Type: article in journal/newspaper
Language: unknown
DOI: 10.3389/fnins.2021.611926
DOI: 10.3389/fnins.2021.611926/full
Availability: https://doi.org/10.3389/fnins.2021.611926; https://www.frontiersin.org/articles/10.3389/fnins.2021.611926/full
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.36C7F343
Database: BASE