| Title: |
P-530. Mortality among U.S. Children |
| Authors: |
baker, Jiana; Taylor, Christopher A; Milucky, Jennifer; Patel, Kadam; Patton, Monica E P; Chai, Shua J; Plano, Julie; Openo, Kyle P P; Ryan, Patricia A; Reeg, Elizabeth; D’Heilly, Paige; Solhtalab, Dominic; Rowe, Adam; Bushey, Sophrena; Sutton, Melissa; Olsen, Kristen; Havers, Fiona P; Wang, Dennis |
| Source: |
Open Forum Infectious Diseases ; volume 13, issue Supplement_1 ; ISSN 2328-8957 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2026 |
| Description: |
Background Pediatric COVID-19 hospitalizations have been well-described, but pediatric COVID-19-associated mortality data are limited. Methods COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) conducts population-based surveillance for laboratory-confirmed COVID-19 hospitalizations in 12 states. After excluding trauma-related admissions, medical charts among children aged < 18 years hospitalized during March 2020–September 2023 were abstracted. Children who died in-hospital or within 30 days of discharge were identified by matching cases with death certificates to describe pediatric COVID-19-associated mortality. Results Among 12,779 hospitalized children with complete chart abstraction, 88 (0.7%) died, including 66 (75.0%) in-hospital deaths and 22 (25.0%) deaths that occurred ≤30 days post-discharge (Figure). Thirty-two percent of children who died were < 1 year old and 23% were < 6 months old. Comparing children who died and those who survived, there were no significant differences in age or sex. A higher proportion of children who died than those who survived were Hispanic (37.5% vs 28.5%), while a lower proportion of children who died were non-Hispanic White (22.7% vs 33.1%) (p< 0.001 for overall racial differences) (Table 1). Compared with children who survived, children who died were more likely to have ≥1 (81.8% vs 51.1%) or ≥2 (52.3% vs 23.3%) underlying medical conditions, including neurological (37.5% vs 15.5%), chronic lung (27.3% vs 19.8%), and cardiovascular diseases (17.0% vs 7.0%) (p< 0.001 for all). Among COVID-19 vaccine-eligible children, 93.8% of those who died and 91.6% of those who survived were not up-to-date with COVID-19 vaccine recommendations (Table 2). Conclusion While COVID-19-associated pediatric hospitalizations resulting in death were rare, most were among children with comorbidities and COVID-19 vaccine-eligible children who were not up-to-date with vaccination, indicating missed opportunities to prevent severe ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ofid/ofaf695.745 |
| Availability: |
https://doi.org/10.1093/ofid/ofaf695.745; https://academic.oup.com/ofid/article-pdf/13/Supplement_1/ofaf695.745/66346603/ofaf695.745.pdf |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.37370497 |
| Database: |
BASE |