| Title: |
Staphylococcus epidermidis bloodstream infections are a cause of septic shock in intensive care unit patients |
| Authors: |
Demiselle, J. (Julien); Meyer, P. (Pierre); Lavigne, T. (Thierry); Kaurin, J. (Julian); Merdji, H. (Hamid); Schenck, M. (Maleka); Studer, A. (Antoine); Janssen-Langenstein, R. (Ralf); Helms, J. (Julie); Hoellinger, B. (Baptiste); Castelain, V. (Vincent); Grillon, A. (Antoine); Schneider, F. (Francis); Meziani, F. (Ferhat); Clere-Jehl, R. (Raphaël) |
| Publication Year: |
2023 |
| Subject Terms: |
Sciences du Vivant [q-bio]/Médecine humaine et pathologie |
| Description: |
Objectives: Staphylococcus epidermidis (SE) is a supposedly low-virulence agent, which may cause proven bloodstream infections (BSIs), with little-known consequences on intensive care unit (ICU) patients. We aimed at studying ICU patients diagnosed with BSIs caused by SE (SE-BSIs). Methods: We constituted a retrospective cohort in two medical ICUs. SE-BSIs were defined by two or more independent SE-positive blood cultures of the same strain, within 48 hours, without concurrent infection. Results: We included 59 patients; 58% were men (n = 34), with median age of 67 (interquartile range 60-74) years and a simplified acute physiology score II of 59 (36-74) points, and 56% were immunocompromised (n = 33). Among the 37 (63%) patients requiring norepinephrine initiation or increase at the onset of SE-BSI versus patients not requiring vasopressors (37%; n = 22), concomitant arterial lactate levels reached 2.8 (1.9-5.8) versus 1.5 (1.3-2.2) mmol/l (P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Availability: |
https://linkinghub.elsevier.com/retrieve/pii/S1201971223006653 |
| Rights: |
Paternité - Pas d'utilisation commerciale - Pas de modification [CC] [BY] [NC] [ND] ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.376D1256 |
| Database: |
BASE |