| Title: |
P1220 Gender Identity and Inflammatory Bowel Disease: A National Bioresource Study Reveals Delayed Diagnosis, Greater Comorbidity and Poorer Quality of Life |
| Authors: |
Colwill, M; Pollok, R; Hall, R; Povlsen, S; Seal, L; Poullis, A |
| Source: |
Journal of Crohn’s and Colitis ; volume 20, issue Supplement_1 ; ISSN 1873-9946 1876-4479 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2026 |
| Description: |
Background Transgender or gender non-conforming (TGNC) individuals frequently experience stigma and poor health outcomes, have high rates of comorbidity, express dissatisfaction in healthcare and are under-represented in healthcare research.[1,2] Despite greater societal awareness of gender identity, little is known about the interplay between a minority gender identity and chronic disease. Inflammatory bowel disease (IBD) is a common chronic immune mediated disorder of the gastrointestinal tract associated with significant physical and psychological morbidity and can significantly impact upon quality of life. There is extremely limited data on the implications of identifying as TGNC and suffering from IBD (TGNC-IBD) particularly with regards to the impact upon time to diagnosis, disease outcomes such as rates of surgery, and quality of life. Methods A questionnaire, designed in collaboration with TGNC-IBD individuals, was distributed through the NIHR IBD Bioresource in the United Kingdom to approximately 47,000 individuals. Data was collected from adult individuals identifying as TGNC via on online portal on demographics, IBD and other medical history and quality of life indices. Data was also collected from an age and sex matched cisgender control cohort. Continuous and ordinal variables were compared with the Mann-Whitney test, categorical with chi-square test. Results 39 individuals identified as TGNC and provided survey responses, demographic details are in table 1. Mean time to diagnosis from the onset of symptoms was 26.5 months compared to 24.0 in the control group (p = 0.70), rate of a history of hospitalisation for IBD was 62.3% compared to 53.9% (Odds ratio (OR) 1.44 p = 0.47), and rates of history of surgery for IBD were 28.6% compared to 21.6% in controls (OR 1.44, p = 0.45) (figure 1). A concurrent psychiatric diagnosis was reported in 79% of TGNC-IBD respondents compared to 50% of controls (p = 0.0024). TGNC-IBD individuals reported a greater negative impact of their IBD on their normal ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ecco-jcc/jjaf231.1401 |
| Availability: |
https://doi.org/10.1093/ecco-jcc/jjaf231.1401; https://academic.oup.com/ecco-jcc/article-pdf/20/Supplement_1/jjaf231.1401/66502835/jjaf231.1401.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.377DF88C |
| Database: |
BASE |