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Outcomes of patients admitted to the intensive care unit for complications of hypertensive disorders of pregnancy at a South African tertiary hospital – a 4-year retrospective review

Title: Outcomes of patients admitted to the intensive care unit for complications of hypertensive disorders of pregnancy at a South African tertiary hospital – a 4-year retrospective review
Authors: Gama, S; Sebitloane, M; de Vasconcellos, K
Source: Southern African Journal of Critical Care; Vol. 35 No. 2 (2019); 62-69 ; 2078-676X ; 1562-8264
Publisher Information: Southern African Journal of Critical Care
Publication Year: 2023
Collection: AJOL - African Journals Online
Subject Terms: Hypertensive disorders of pregnancy; intensive care unit; mortality; neurological outcomes; eclampsia; human immunodeficiency virus
Description: Background. Hypertensive disorders of pregnancy (HDP) are a major cause of maternal mortality and adverse outcomes. A previous study in the intensive care unit (ICU) at King Edward VIII Hospital, Durban, South Africa, in 2000 found 10.5% mortality among eclampsia patients. Objectives. To describe the mortality and adverse neurological outcomes associated with HDP in a tertiary ICU, compare these with results from 2000 and describe factors associated therewith. Methods. The data of 85 patients admitted with HDP to ICU at King Edward VIII Hospital from 2010 to 2013 were retrospectively reviewed. Mortality and adverse neurological outcome (Glasgow Coma Scale (GCS) ≤14 on discharge from ICU) were assessed. Two sets of analyses were conducted. The first compared those alive on discharge from ICU with those who died in ICU. The second compared good neurological outcome with poor outcome (adverse neurological outcome, or death). Results. The mortality was 11.6%, and overall, 9% had adverse neurological outcomes. There was no significant difference in mortality between patients with eclampsia in 2010 - 2013 (11.0%) and those in 2000 (10.5%) (p=0.9). Factors associated with mortality were: intra- or postpartum onset of seizures; twins; failure to perform operative delivery when indicated; lowest GCS score
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
Relation: https://www.ajol.info/index.php/sajcc/article/view/246464/233140; https://www.ajol.info/index.php/sajcc/article/view/246464
Availability: https://www.ajol.info/index.php/sajcc/article/view/246464
Accession Number: edsbas.39BB705B
Database: BASE