| Title: |
Testicular tumours in children: a single-centre experience |
| Authors: |
Ali, Sajid; Latif, Tariq; Sheikh, Muhammad Ali; Perveen, Shazia; Bilal, Muhammad; Sarwar, Albash |
| Source: |
Singapore Medical Journal ; ISSN 0037-5675 2737-5935 |
| Publisher Information: |
Medknow |
| Publication Year: |
2023 |
| Description: |
Introduction: Testicular tumours in childhood have diverse characteristics for different age ranges. This study aimed to describe the pattern, presentation and outcomes of primary testicular tumours in a paediatric population. Methods: A retrospective study was conducted from January 2010 to December 2020 on children (≤18 years) with a diagnosis of primary testicular tumour. Baseline demographics, clinical characteristics, pathology, treatment and outcomes of these patients were analysed. The data were entered into IBM SPSS Statistics version 20.0. Chi-square test and Fisher’s exact test were applied to find the statistical significance, which was set at P value ≤ 0.05. Results: The study included 115 males, with 85 (73.9%) patients in the prepubertal age range with a mean age of 2.53 ± 2.06 years and 30 (26.1%) patients in the postpubertal group with a mean age of 15.73 ± 1.25 years. Yolk sac tumour was the most common (62.6%) histological subtype. Majority (46.1%) of patients had stage I disease on presentation, while 29.6% had stage IV disease. All patients underwent upfront high inguinal radical orchiectomy, which was followed by platinum-based adjuvant chemotherapy in 67% of the patients. The five-year event-free survival and overall survival for all patients were 75% and 91%, respectively. Conclusion: Primary testicular tumours follow a bimodal age distribution pattern. Majority of patients can be cured with platinum-based chemotherapy despite having advanced disease at presentation. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.4103/singaporemedj.smj-2021-380 |
| DOI: |
10.4103/singaporemedj.SMJ-2021-380 |
| Availability: |
https://doi.org/10.4103/singaporemedj.smj-2021-380; https://journals.lww.com/10.4103/singaporemedj.SMJ-2021-380 |
| Accession Number: |
edsbas.3A66A96A |
| Database: |
BASE |