| Title: |
Vaccine immunity in patients with 22q11.2 microdeletion syndrome |
| Authors: |
Farpour, Leïla Luz Cerise; Gualtieri, Renato; Kotalova, Tereza; Lemaitre, Barbara; Ducreux, Julie; Arm-Vernez, Isabelle; Eliez, Stéphan; Blanchard Rohner, Géraldine |
| Source: |
ISSN: 0905-6157 ; Pediatric allergy and immunology, vol. 36, no. 2 (2025) e70043. |
| Publication Year: |
2025 |
| Collection: |
Université de Genève: Archive ouverte UNIGE |
| Subject Terms: |
info:eu-repo/classification/ddc/616.89; info:eu-repo/classification/ddc/616; info:eu-repo/classification/ddc/616.07; info:eu-repo/classification/ddc/618; 22q11.2 microdeletion syndrome; 31 vaccination; Immunology workup; Vaccine immunity; Humans; Female; Male; Child; Preschool; Adolescent; Prospective Studies; DiGeorge Syndrome / immunology; Infant; Vaccination; Young Adult; SARS-CoV-2 / immunology; COVID-19 / immunology; Adult; Vaccines / immunology |
| Description: |
Background: Patients with microdeletion 22q11.2 syndrome (MDS) exhibit immunological defects, characterized by abnormalities in the development of the thymus, which plays a crucial role in T-cell maturation and immune response. As a result, these patients may have impaired adaptive immunity, with decreased responses to vaccination. Methods: This was a prospective observational study. Vaccine serology (tetanus, diphtheria, Haemophilus influenzae type b for children |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/39927887; unige:183822 |
| Availability: |
https://archive-ouverte.unige.ch/unige:183822 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.3ACE93A0 |
| Database: |
BASE |