| Title: |
EFFICACY AND SAFETY OF BOCEPREVIR-BASED THERAPY IN HCVG1 TREATMENT-EXPERIENCED PATIENTS WITH ADVANCED FIBROSIS/CIRRHOSIS: THE ITALIAN AND SPANISH NPP EARLY ACCESS PROGRAM |
| Authors: |
Bruno, S; Bollani, S.; Pascasio, JM; Zignego, AL; DI MARCO, Vito; Magni, C; Rizzetto, M; Ciancio, A; Alberti, A; Piovesan, S; Mangia, A; De la Revilla, J; Larrubia, JR; Gea, F; Babudieri, S; Perez Alvarez, R; Colletta, C; Barcena, R; Forns, X; Romero Gomez, M; Koch, M; Massari, M; Caremani, M; Crespo, J; Navarro, JM; Arenas, J; Delgado, MB; Pirisi, M; Zuin, M; LICATA, Anna; Mazzotta, F; Colombo, A; Russello, M; Fermandez, I; Santantonio, T; Fernandez Rodriguez, CM; Farina, F; Ruiz Antoran, B; Maisonneuve, P; CRAXI, Antonio; Calleja, JL |
| Contributors: |
Bruno, S.; Bollani, S.; Pascasio, J.; Zignego, A.; Di Marco, V.; Magni, C.; Rizzetto, M.; Ciancio, A.; Alberti, A.; Piovesan, S.; Mangia, A.; De La Revilla, J.; Larrubia, J.; Gea, F.; Babudieri, S.; Perez Alvarez, R.; Colletta, C.; Barcena, R.; Forns, X.; Romero Gomez, M.; Koch, M.; Massari, M.; Caremani, M.; Crespo, J.; Navarro, J.; Arenas, J.; Delgado, M.; Pirisi, M.; Zuin, M.; Licata, A.; Mazzotta, F.; Colombo, A.; Russello, M.; Fermandez, I.; Santantonio, T.; Fernandez Rodriguez, C.; Farina, F.; Ruiz Antoran, B.; Maisonneuve, P.; Craxi, A.; Calleja, J. |
| Publisher Information: |
Elsevier Science Limited |
| Publication Year: |
2014 |
| Collection: |
IRIS Università degli Studi di Palermo |
| Subject Terms: |
HEPATITIS C; CIRRHOSIS; CHRONIC HCV; Settore MED/09 - Medicina Interna; Settore MED/12 - Gastroenterologia |
| Description: |
Background and Aims: To maximize cost/efficay of boceprevirbased triple therapy (BOC) in patients with HCV-related advanced fibrosis/cirrhosis. Methods: ITT SVR12, safety and futility rules value were evaluated in the multicenter national Italian and Spanish early access Name- Patient-Program which includes treatment-experienced patients with HCVG1-related advanced fibrosis/cirrhosis (Metavir F3/4) treated with BOC in both countries. Results: 402 patients (mean age 55 years; range 22–75), 316 (78.6%) G1b, 255 (63.4%) F4, 60 (30.9%) with oesophageal varices, 137 (34.1%) relapsers, 95 (23.6%) partial and 168 (41.8%) null responders were enrolled. Platelets count |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:000362828600574; 49° INTERNATIONAL LIVER CONGRESS 2014; firstpage:S470; lastpage:S470; numberofpages:1; journal:JOURNAL OF HEPATOLOGY; https://hdl.handle.net/10447/103571 |
| Availability: |
https://hdl.handle.net/10447/103571 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.3B3CD23B |
| Database: |
BASE |