| Title: |
Changes in surgical revascularization strategy after fractional flow reserve |
| Authors: |
Fournier S.; Toth G. G.; De Bruyne B.; Kala P.; Ribichini F. L.; Casselman F.; Ramos R.; Piroth Z.; Piccoli A.; Penicka M.; Mates M.; Nemec P.; Van Praet F.; Stockman B.; Degriek I.; Pellicano M.; Barbato E. |
| Contributors: |
Fournier, S.; Toth, G. G.; De Bruyne, B.; Kala, P.; Ribichini, F. L.; Casselman, F.; Ramos, R.; Piroth, Z.; Piccoli, A.; Penicka, M.; Mates, M.; Nemec, P.; Van Praet, F.; Stockman, B.; Degriek, I.; Pellicano, M.; Barbato, E. |
| Publisher Information: |
John Wiley and Sons Inc |
| Publication Year: |
2021 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
coronary artery disease; coronary bypass graft; fractional flow reserve |
| Description: |
Aims: In the randomized GRAFFITI trial, surgeons drew their strategy based on coronary angiography. When patients were randomized to fractional flow reserve (FFR)-guidance, surgeons were informed of the FFR values and asked to redraw their strategy. The aim of this study was to investigate the changes induced by FFR knowledge. Methods and Results: The intended and performed strategy (before and after FFR) were compared. Among 172 patients, 84 with 300 lesions were randomized to the FFR-guided group. The intended strategy was to bypass 236 stenoses:108 with a venous and 128 with an arterial graft. After disclosing FFR, a change in strategy occurred in 64 lesions (21.3%) of 48 (55%) patients. Among 64 lesions for which the intended strategy was medical therapy, 16 (25%) were bypassed after disclosing FFR. The number of procedures with >1 venous graft planned was significantly reduced from 37 to 27 patients (p =.031). The proportion of on-pump surgery was significantly reduced from 71 to 61 patients (p =.006). The rates of clinical events at 1 year were similar between patients with or without at least one change in strategy. Discussion: FFR-guided CABG is associated with a simplified surgical procedure in 55% of the patients, with similar clinical outcomes. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:000638603200001; volume:98; issue:3; firstpage:351; lastpage:355; numberofpages:5; journal:CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS; https://hdl.handle.net/11573/1700457 |
| DOI: |
10.1002/ccd.29694 |
| Availability: |
https://hdl.handle.net/11573/1700457; https://doi.org/10.1002/ccd.29694 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.3B933AA2 |
| Database: |
BASE |