| Title: |
Non‑curative treatment of patients with oral tongue squamous‑cell carcinoma |
| Authors: |
Mroueh, R. (R.); Haapaniemi, A. (A.); Saarto, T. (T.); Grönholm, L. (L.); Grénman, R. (R.); Salo, T. (T.); Mäkitie, A. A. (A. A.) |
| Publisher Information: |
Springer Nature |
| Publication Year: |
2019 |
| Collection: |
Jultika - University of Oulu repository / Oulun yliopiston julkaisuarkisto |
| Subject Terms: |
Head and neck cancer; chemotherapy; death; end of life; palliation; palliative care; quality of life; surgery; tongue cancer |
| Description: |
Purpose: Late-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival. Methods: All patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005–2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan–Meier method in this population-based study. Results: Eighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7 months (median 2 and range 0–26). Conclusions: Due to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Availability: |
http://urn.fi/urn:nbn:fi-fe2019061220152 |
| Rights: |
info:eu-repo/semantics/openAccess ; © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licen ses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. ; https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.3C5A2CB5 |
| Database: |
BASE |