| Title: |
Pooled surveillance testing for asymptomatic SARS-CoV-2 infections at a Veterinary Teaching Hospital College, University of Minnesota, December 2020–April 2021 |
| Authors: |
Mladonicky, Janice; Bedada, Addisalem; Yoder, Colin; VanderWaal, Kimberly; Torrison, Jerry; Wells, Scott J. |
| Source: |
Frontiers in Public Health ; volume 10 ; ISSN 2296-2565 |
| Publisher Information: |
Frontiers Media SA |
| Publication Year: |
2022 |
| Collection: |
Frontiers (Publisher - via CrossRef) |
| Description: |
To evaluate the use of asymptomatic surveillance, we implemented a surveillance program for asymptomatic SARS-CoV-2 infection in a voluntary sample of individuals at the College of Veterinary Medicine at the University of Minnesota. Self-collected anterior nasal samples were tested using real time reverse transcription-polymerase chain reaction (RT-PCR), in a 5:1 pooled testing strategy, twice weekly for 18 weeks. Positive pools were deconvoluted into individual tests, revealing an observed prevalence of 0.07% (3/4,525). Pooled testing allowed for large scale testing with an estimated cost savings of 79.3% and modeling demonstrated this testing strategy prevented up to 2 workplace transmission events, averting up to 4 clinical cases. At the study endpoint, antibody testing revealed 80.7% of participants had detectable vaccine antibody levels while 9.6% of participants had detectable antibodies to natural infection. |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| DOI: |
10.3389/fpubh.2022.879107 |
| DOI: |
10.3389/fpubh.2022.879107/full |
| Availability: |
https://doi.org/10.3389/fpubh.2022.879107; https://www.frontiersin.org/articles/10.3389/fpubh.2022.879107/full |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.3D9D3DF9 |
| Database: |
BASE |